TY - JOUR
T1 - Surface functionalization of biomedical Ti-6Al-7Nb alloy by liquid metal dealloying
AU - Okulov, Ilya Vladimirovich
AU - Joo, Soo Hyun
AU - Okulov, Artem Vladimirovich
AU - Volegov, Alexey Sergeevich
AU - Luthringer, Bérengère
AU - Willumeit-Römer, Regine
AU - Zhang, Laichang
AU - Mädler, Lutz
AU - Eckert, Jürgen
AU - Kato, Hidemi
N1 - Funding Information:
Supervision, I.V.O., R.W.-R., L.Z., L.M., J.E. and H.K.; Validation, I.V.O., S.-H.J., and B.L.; Writing – original draft, I.V.O. and B.L.; Writing – review & editing, all. All authors have read and agreed to the published version Funding: The financial support was provided by the German Science Foundation under the Leibniz Program of the manuscript. (Grant MA 3333/13-1), by the European Research Council (ERC) under the ERC Advanced Grant INTELHYB (grant Funding: The financial support was provided by the German Science Foundation under the Leibniz Program Ministry of Science and Higher Education of the Russian Federation, in the framework of the Increase Competitiveness (Grant MA 3333/13-1), by the European Research Council (ERC) under the ERC Advanced Grant INTELHYB Program of NUST «MISiS» (grant number K2-2020-020). I.V.O. is grateful for the financial support provided by the International Collaboration Center, Institute for Materials Research (ICC-IMR), Tohoku University, Japan. 02.A03.21.0006), and the Ministry of Science and Higher Education of the Russian Federation, in the framework Conflicts of Interest: The authors declare no conflict of interest. of the Increase Competitiveness Program of NUST «MISiS» (grant number K2-2020-020). I.V.O. is grateful for the financial support provided by the International Collaboration Center, Institute for Materials Research (ICC-IMR), Tohoku University, Japan.
Funding Information:
The financial support was provided by the German Science Foundation under the Leibniz Program (Grant MA 3333/13-1), by the European Research Council (ERC) under the ERC Advanced Grant INTELHYB (grant ERC-2013-ADG-340025), by Act 211 Government of the Russian Federation (contract number 02.A03.21.0006), and the Ministry of Science and Higher Education of the Russian Federation, in the framework of the Increase Competitiveness Program of NUST ?MISiS? (grant number K2-2020-020). I.V.O. is grateful for the financial support provided by the International Collaboration Center, Institute for Materials Research (ICC-IMR), Tohoku University, Japan.
Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2020/8
Y1 - 2020/8
N2 - Surface functionalization is an effective approach to change the surface properties of a material to achieve a specific goal such as improving the biocompatibility of the material. Here, the surface of the commercial biomedical Ti-6Al-7Nb alloy was functionalized through synthesizing of a porous surface layer by liquid metal dealloying (LMD). During LMD, the Ti-6Al-7Nb alloy is immersed in liquid magnesium (Mg) and both materials react with each other. Particularly, aluminum (Al) is selectively dissolved from the Ti-6Al-7Nb alloy into liquid Mg while titanium (Ti) and niobium (Nb) diffuse along the metal/liquid interface to form a porous structure. We demonstrate that the porous surface layer in the Ti-6Al-7Nb alloy can be successfully tailored by LMD. Furthermore, the concentration of harmful Al in this porous layer is reduced by about 48% (from 5.62 ± 0.11 wt.% to 2.95 ± 0.05 wt.%) after 30 min of dealloying at 1150 K. The properties of the porous layer (e.g., layer thickness) can be tuned by varying the dealloying conditions. In-vitro tests suggest improved bone formation on the functionalized porous surface of the Ti-6Al-7Nb alloy.
AB - Surface functionalization is an effective approach to change the surface properties of a material to achieve a specific goal such as improving the biocompatibility of the material. Here, the surface of the commercial biomedical Ti-6Al-7Nb alloy was functionalized through synthesizing of a porous surface layer by liquid metal dealloying (LMD). During LMD, the Ti-6Al-7Nb alloy is immersed in liquid magnesium (Mg) and both materials react with each other. Particularly, aluminum (Al) is selectively dissolved from the Ti-6Al-7Nb alloy into liquid Mg while titanium (Ti) and niobium (Nb) diffuse along the metal/liquid interface to form a porous structure. We demonstrate that the porous surface layer in the Ti-6Al-7Nb alloy can be successfully tailored by LMD. Furthermore, the concentration of harmful Al in this porous layer is reduced by about 48% (from 5.62 ± 0.11 wt.% to 2.95 ± 0.05 wt.%) after 30 min of dealloying at 1150 K. The properties of the porous layer (e.g., layer thickness) can be tuned by varying the dealloying conditions. In-vitro tests suggest improved bone formation on the functionalized porous surface of the Ti-6Al-7Nb alloy.
KW - Biocompatibility
KW - Biomaterial
KW - Dealloying
KW - Porous surface
KW - Surface functionalization
UR - http://www.scopus.com/inward/record.url?scp=85090641060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85090641060&partnerID=8YFLogxK
U2 - 10.3390/nano10081479
DO - 10.3390/nano10081479
M3 - Article
AN - SCOPUS:85090641060
SN - 2079-4991
VL - 10
SP - 1
EP - 12
JO - Nanomaterials
JF - Nanomaterials
IS - 8
M1 - 1479
ER -