Switching Modulation for Protein Labeling with Activatable Fluorescent Probes

Kalyan K. Sadhu, Shin Mizukami, Yuichiro Hori, Kazuya Kikuchi

Research output: Contribution to journalShort surveypeer-review

10 Citations (Scopus)


Fluorogenic protein-labeling techniques have been successfully used in live-cell imaging. Fluorescence derived from specific labeling can monitor the localization of proteins. Newly developed chemical techniques have addressed such specific incorporation of probes in the physiological environment. We conclude that some recent promising switching techniques should provide further molecular functional exploitation in vivo.

Original languageEnglish
Pages (from-to)1299-1308
Number of pages10
Issue number9
Publication statusPublished - 2011 Jun 14


  • Biotechnology
  • Dyes
  • Fluorescence spectroscopy
  • Fluorescent probes
  • Protein labeling


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