Syntheses of GM4 and GM3 Intermediates via Alkylation and Subsequent Intramolecular Glycosidation of 2-Alkoxy-2-phenylthioacetate

Takashi Takahashi; Hirokazu Tsukamoto; Haruo Yamada

doi:10.1021/ol990245k

Syntheses of G_M4 and G_M3 Intermediates via Alkylation and Subsequent Intramolecular Glycosidation of 2-Alkoxy-2-phenylthioacetate

Takashi Takahashi, Hirokazu Tsukamoto, Haruo Yamada

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

(Matrix presented) We developed a new method for α-glycoside formation of sialyl conjugates based on alkylation and subsequent intramolecular glycosidation of 2-alkoxy-2-phenylthioacetate. By this method we succeeded in the syntheses of G_M4 and G_M3 intermediates.

Original language	English
Pages (from-to)	1885-1887
Number of pages	3
Journal	Organic letters
Volume	1
Issue number	12
DOIs	https://doi.org/10.1021/ol990245k
Publication status	Published - 1999 Dec 16

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol990245k

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title = "Syntheses of GM4 and GM3 Intermediates via Alkylation and Subsequent Intramolecular Glycosidation of 2-Alkoxy-2-phenylthioacetate",

abstract = "(Matrix presented) We developed a new method for α-glycoside formation of sialyl conjugates based on alkylation and subsequent intramolecular glycosidation of 2-alkoxy-2-phenylthioacetate. By this method we succeeded in the syntheses of GM4 and GM3 intermediates.",

author = "Takashi Takahashi and Hirokazu Tsukamoto and Haruo Yamada",

year = "1999",

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journal = "Organic Letters",

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T1 - Syntheses of GM4 and GM3 Intermediates via Alkylation and Subsequent Intramolecular Glycosidation of 2-Alkoxy-2-phenylthioacetate

AU - Takahashi, Takashi

AU - Tsukamoto, Hirokazu

AU - Yamada, Haruo

PY - 1999/12/16

Y1 - 1999/12/16

N2 - (Matrix presented) We developed a new method for α-glycoside formation of sialyl conjugates based on alkylation and subsequent intramolecular glycosidation of 2-alkoxy-2-phenylthioacetate. By this method we succeeded in the syntheses of GM4 and GM3 intermediates.

AB - (Matrix presented) We developed a new method for α-glycoside formation of sialyl conjugates based on alkylation and subsequent intramolecular glycosidation of 2-alkoxy-2-phenylthioacetate. By this method we succeeded in the syntheses of GM4 and GM3 intermediates.

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JO - Organic Letters

JF - Organic Letters

IS - 12

ER -

Syntheses of G_M4 and G_M3 Intermediates via Alkylation and Subsequent Intramolecular Glycosidation of 2-Alkoxy-2-phenylthioacetate

Abstract

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