Abstract
Watersoluble nucleic acid analogs containing L- or D-serine as a spacer were synthesized. Thymine was used as nucleic acid bases of these analogs. The base contents of these analogs were 93-94%. These analogs were found to form stable polymer complexes with Poly A or DNA by specific base-base interaction, which were observed from hypochromicity of UV spectra. In both cases, the maximum hypochromicity values of PEI-L-Ser-Thy were higher than that of PEI-D-Ser-Thy.
| Original language | English |
|---|---|
| Pages (from-to) | 115-116 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series |
| Issue number | 27 |
| Publication status | Published - 1992 |