3-Substituted 5-(tributylstannyl)isoxazoles were synthesized in good yields by the 1,3-dipolar cycloaddition reaction of ethynyltributylstannane with nitrile oxides generated in situ. 3-Methyl-5-(tributylstannyl)isoxazole was easily converted to the corresponding 5-benzoyl- and 5-arylisoxazoles by the palladium-catalyzed reaction.
|Number of pages||2|
|Publication status||Published - 1989 Jan 1|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry