Synthesis and reactions of 5-(tributylstannyl)isoxazoles

Yoshinori Kondo; Daishi Uchiyama; Takao Sakamoto; Hiroshi Yamanaka

doi:10.1016/S0040-4039(01)80702-4

Synthesis and reactions of 5-(tributylstannyl)isoxazoles

Yoshinori Kondo, Daishi Uchiyama, Takao Sakamoto, Hiroshi Yamanaka

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

3-Substituted 5-(tributylstannyl)isoxazoles were synthesized in good yields by the 1,3-dipolar cycloaddition reaction of ethynyltributylstannane with nitrile oxides generated in situ. 3-Methyl-5-(tributylstannyl)isoxazole was easily converted to the corresponding 5-benzoyl- and 5-arylisoxazoles by the palladium-catalyzed reaction.

Original language	English
Pages (from-to)	4249-4250
Number of pages	2
Journal	Tetrahedron Letters
Volume	30
Issue number	32
DOIs	https://doi.org/10.1016/S0040-4039(01)80702-4
Publication status	Published - 1989 Jan 1

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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abstract = "3-Substituted 5-(tributylstannyl)isoxazoles were synthesized in good yields by the 1,3-dipolar cycloaddition reaction of ethynyltributylstannane with nitrile oxides generated in situ. 3-Methyl-5-(tributylstannyl)isoxazole was easily converted to the corresponding 5-benzoyl- and 5-arylisoxazoles by the palladium-catalyzed reaction.",

author = "Yoshinori Kondo and Daishi Uchiyama and Takao Sakamoto and Hiroshi Yamanaka",

year = "1989",

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T1 - Synthesis and reactions of 5-(tributylstannyl)isoxazoles

AU - Kondo, Yoshinori

AU - Uchiyama, Daishi

AU - Sakamoto, Takao

AU - Yamanaka, Hiroshi

PY - 1989/1/1

Y1 - 1989/1/1

N2 - 3-Substituted 5-(tributylstannyl)isoxazoles were synthesized in good yields by the 1,3-dipolar cycloaddition reaction of ethynyltributylstannane with nitrile oxides generated in situ. 3-Methyl-5-(tributylstannyl)isoxazole was easily converted to the corresponding 5-benzoyl- and 5-arylisoxazoles by the palladium-catalyzed reaction.

AB - 3-Substituted 5-(tributylstannyl)isoxazoles were synthesized in good yields by the 1,3-dipolar cycloaddition reaction of ethynyltributylstannane with nitrile oxides generated in situ. 3-Methyl-5-(tributylstannyl)isoxazole was easily converted to the corresponding 5-benzoyl- and 5-arylisoxazoles by the palladium-catalyzed reaction.

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U2 - 10.1016/S0040-4039(01)80702-4

DO - 10.1016/S0040-4039(01)80702-4

M3 - Article

AN - SCOPUS:0003134393

SN - 0040-4039

VL - 30

SP - 4249

EP - 4250

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

ER -

Synthesis and reactions of 5-(tributylstannyl)isoxazoles

Abstract

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