TY - JOUR
T1 - Synthesis and spectroscopic properties of new phthalocyanine complexes with potentially combined photodynamic activity and cytotoxicity for photodynamic therapy
AU - Nemykin, V. N.
AU - Mytsyk, V. M.
AU - Volkov, S. V.
AU - Kobayashi, N.
N1 - Funding Information:
V.N.N. is grateful to JSPS for financial support (grant P98418). This work was partially financed by an INTAS grant (number 97-0791). N.K. was supported partially by a Grant-in-Aid for Scientific Research (B) from the Ministry of Education, Science, Sports, and Culture, Japan (number 60124575).
PY - 2000
Y1 - 2000
N2 - The reaction of zinc tetrakis(3-pyridyloxy)phthalocyanine (1) with NH4[PtNH3Cl3] leads to zinc tetrakis(cis-[3-oxypyridyl]-N]amminedichloroplatinum(II))phthalocyanine (2), while the reaction of 1 with cis-Pt (DMSO)2Cl2 or 2 with DMSO forms zinc tetrakis(cis-[(3-oxypyridyl)-N]dichloro[sulfinylbis(methane)-S]platinum(II))p hthalocyanine (3). The new phthalocyanines 2 and 3, with potentially combined photodynamic activity and cytotoxicity, have been characterized by means of electronic, 1H NMR and IR spectroscopies. Copyright (C) 2000 John Wiley and Sons, Ltd.
AB - The reaction of zinc tetrakis(3-pyridyloxy)phthalocyanine (1) with NH4[PtNH3Cl3] leads to zinc tetrakis(cis-[3-oxypyridyl]-N]amminedichloroplatinum(II))phthalocyanine (2), while the reaction of 1 with cis-Pt (DMSO)2Cl2 or 2 with DMSO forms zinc tetrakis(cis-[(3-oxypyridyl)-N]dichloro[sulfinylbis(methane)-S]platinum(II))p hthalocyanine (3). The new phthalocyanines 2 and 3, with potentially combined photodynamic activity and cytotoxicity, have been characterized by means of electronic, 1H NMR and IR spectroscopies. Copyright (C) 2000 John Wiley and Sons, Ltd.
KW - Heterometallic polynuclear phthalocyanines
KW - Photodynamic therapy
KW - Platinum
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U2 - 10.1002/1099-1409(200008)4:5<551::AID-JPP270>3.0.CO;2-L
DO - 10.1002/1099-1409(200008)4:5<551::AID-JPP270>3.0.CO;2-L
M3 - Article
AN - SCOPUS:0033653667
SN - 1088-4246
VL - 4
SP - 551
EP - 554
JO - Journal of Porphyrins and Phthalocyanines
JF - Journal of Porphyrins and Phthalocyanines
IS - 5
ER -