Synthesis and transfection capability of multi-functionalized fullerene polyamine

Hiroyuki Isobe; Naoki Tomita; Shigeki Jinno; Hiroto Okayama; Eiichi Nakamura

doi:10.1246/cl.2001.1214

Synthesis and transfection capability of multi-functionalized fullerene polyamine

Hiroyuki Isobe, Naoki Tomita, Shigeki Jinno, Hiroto Okayama, Eiichi Nakamura

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

A new fullerene transfection reagent bearing multiple-functional groups has been synthesized by diastereoselective double cycloaddition reaction. The highly oxygenated reagent transfers extra-cellular DNA into mammalian cells with the efficiency comparable to that of a nor-analogue.

Original language	English
Pages (from-to)	1214-1215
Number of pages	2
Journal	Chemistry Letters
Issue number	12
DOIs	https://doi.org/10.1246/cl.2001.1214
Publication status	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.2001.1214

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title = "Synthesis and transfection capability of multi-functionalized fullerene polyamine",

abstract = "A new fullerene transfection reagent bearing multiple-functional groups has been synthesized by diastereoselective double cycloaddition reaction. The highly oxygenated reagent transfers extra-cellular DNA into mammalian cells with the efficiency comparable to that of a nor-analogue.",

author = "Hiroyuki Isobe and Naoki Tomita and Shigeki Jinno and Hiroto Okayama and Eiichi Nakamura",

year = "2001",

doi = "10.1246/cl.2001.1214",

language = "English",

pages = "1214--1215",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Chemical Society of Japan",

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T1 - Synthesis and transfection capability of multi-functionalized fullerene polyamine

AU - Isobe, Hiroyuki

AU - Tomita, Naoki

AU - Jinno, Shigeki

AU - Okayama, Hiroto

AU - Nakamura, Eiichi

PY - 2001

Y1 - 2001

N2 - A new fullerene transfection reagent bearing multiple-functional groups has been synthesized by diastereoselective double cycloaddition reaction. The highly oxygenated reagent transfers extra-cellular DNA into mammalian cells with the efficiency comparable to that of a nor-analogue.

AB - A new fullerene transfection reagent bearing multiple-functional groups has been synthesized by diastereoselective double cycloaddition reaction. The highly oxygenated reagent transfers extra-cellular DNA into mammalian cells with the efficiency comparable to that of a nor-analogue.

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U2 - 10.1246/cl.2001.1214

DO - 10.1246/cl.2001.1214

M3 - Article

AN - SCOPUS:0035528497

SN - 0366-7022

SP - 1214

EP - 1215

JO - Chemistry Letters

JF - Chemistry Letters

IS - 12

ER -

Synthesis and transfection capability of multi-functionalized fullerene polyamine

Abstract

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