Synthesis of 13-methyl[10] (4,6)pyrimidinophane

Takao Sakamoto; Sumiko Nishimura; Yoshinori Kondo; Hiroshi Yamanaka

Synthesis of 13-methyl[10] (4,6)pyrimidinophane

Takao Sakamoto, Sumiko Nishimura, Yoshinori Kondo, Hiroshi Yamanaka

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The palladium-catalyzed reaction of 4,6-diiodo-2-methylpyrimidine with 5-trimethylsilylpent-4-yn-1-ylzinc iodide gave 4,6-bis(5-trimethylsilylpent-4-yn-1-yl)-2-methyl-pyrimidine. Desilylation of the product followed by treatment with cupric acetate gave 13-methyl[10](4,6)pyrimidinophane.

Original language	English
Pages (from-to)	475-478
Number of pages	4
Journal	Heterocycles
Volume	27
Issue number	2
Publication status	Published - 1988 Feb 1

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

Cite this

@article{36c5ef93568d4073bc3751c031563013,

title = "Synthesis of 13-methyl[10] (4,6)pyrimidinophane",

abstract = "The palladium-catalyzed reaction of 4,6-diiodo-2-methylpyrimidine with 5-trimethylsilylpent-4-yn-1-ylzinc iodide gave 4,6-bis(5-trimethylsilylpent-4-yn-1-yl)-2-methyl-pyrimidine. Desilylation of the product followed by treatment with cupric acetate gave 13-methyl[10](4,6)pyrimidinophane.",

author = "Takao Sakamoto and Sumiko Nishimura and Yoshinori Kondo and Hiroshi Yamanaka",

year = "1988",

month = feb,

day = "1",

language = "English",

volume = "27",

pages = "475--478",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "2",

}

TY - JOUR

T1 - Synthesis of 13-methyl[10] (4,6)pyrimidinophane

AU - Sakamoto, Takao

AU - Nishimura, Sumiko

AU - Kondo, Yoshinori

AU - Yamanaka, Hiroshi

PY - 1988/2/1

Y1 - 1988/2/1

N2 - The palladium-catalyzed reaction of 4,6-diiodo-2-methylpyrimidine with 5-trimethylsilylpent-4-yn-1-ylzinc iodide gave 4,6-bis(5-trimethylsilylpent-4-yn-1-yl)-2-methyl-pyrimidine. Desilylation of the product followed by treatment with cupric acetate gave 13-methyl[10](4,6)pyrimidinophane.

AB - The palladium-catalyzed reaction of 4,6-diiodo-2-methylpyrimidine with 5-trimethylsilylpent-4-yn-1-ylzinc iodide gave 4,6-bis(5-trimethylsilylpent-4-yn-1-yl)-2-methyl-pyrimidine. Desilylation of the product followed by treatment with cupric acetate gave 13-methyl[10](4,6)pyrimidinophane.

UR - http://www.scopus.com/inward/record.url?scp=19644371394&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=19644371394&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:19644371394

SN - 0385-5414

VL - 27

SP - 475

EP - 478

JO - Heterocycles

JF - Heterocycles

IS - 2

ER -

Synthesis of 13-methyl[10] (4,6)pyrimidinophane

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this