Synthesis of nano-bio conjugates for drug delivery systems using gas-liquid interfacial discharge plasmas

Toshiro Kaneko; Qiang Chen; Rikizo Hatakeyama

doi:10.3938/jkps.60.929

Synthesis of nano-bio conjugates for drug delivery systems using gas-liquid interfacial discharge plasmas

Toshiro Kaneko, Qiang Chen, Rikizo Hatakeyama

ENG - Electronic Engineering

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Size-controlled gold nanoparticles (AuNPs) covered with DNA are synthesized by using a pulsedriven gas-liquid interfacial discharge plasma (GLIDP) to reduce an aqueous solution of chloroauric acid trihydrate with DNA. The size and the assembly of the AuNPs are found to be easily controlled by changing the DNA concentration in the aqueous solution. The synthesized AuNP-DNA conjugates are forced to be encapsulated into double-walled carbon nanotubes (DWNTs) by superimposing a positive DC voltage on the pulse voltage. The AuNP-DNA-conjugate encapsulated DWNTs can be utilized in drug delivery systems when DNA is used as a drug molecule.

Original language	English
Pages (from-to)	929-932
Number of pages	4
Journal	Journal of the Korean Physical Society
Volume	60
Issue number	6
DOIs	https://doi.org/10.3938/jkps.60.929
Publication status	Published - 2012 Mar

Keywords

DNA
Drug delivery system
Gas-liquid interfacial discharge plasma
Gold nanoparticle

ASJC Scopus subject areas

Physics and Astronomy(all)

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10.3938/jkps.60.929

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title = "Synthesis of nano-bio conjugates for drug delivery systems using gas-liquid interfacial discharge plasmas",

abstract = "Size-controlled gold nanoparticles (AuNPs) covered with DNA are synthesized by using a pulsedriven gas-liquid interfacial discharge plasma (GLIDP) to reduce an aqueous solution of chloroauric acid trihydrate with DNA. The size and the assembly of the AuNPs are found to be easily controlled by changing the DNA concentration in the aqueous solution. The synthesized AuNP-DNA conjugates are forced to be encapsulated into double-walled carbon nanotubes (DWNTs) by superimposing a positive DC voltage on the pulse voltage. The AuNP-DNA-conjugate encapsulated DWNTs can be utilized in drug delivery systems when DNA is used as a drug molecule.",

keywords = "DNA, Drug delivery system, Gas-liquid interfacial discharge plasma, Gold nanoparticle",

author = "Toshiro Kaneko and Qiang Chen and Rikizo Hatakeyama",

note = "Funding Information: The authors thank Mr. T. Miyazaki for his technical assistance. This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology, Japan.",

year = "2012",

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doi = "10.3938/jkps.60.929",

language = "English",

volume = "60",

pages = "929--932",

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TY - JOUR

T1 - Synthesis of nano-bio conjugates for drug delivery systems using gas-liquid interfacial discharge plasmas

AU - Kaneko, Toshiro

AU - Chen, Qiang

AU - Hatakeyama, Rikizo

N1 - Funding Information: The authors thank Mr. T. Miyazaki for his technical assistance. This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology, Japan.

PY - 2012/3

Y1 - 2012/3

N2 - Size-controlled gold nanoparticles (AuNPs) covered with DNA are synthesized by using a pulsedriven gas-liquid interfacial discharge plasma (GLIDP) to reduce an aqueous solution of chloroauric acid trihydrate with DNA. The size and the assembly of the AuNPs are found to be easily controlled by changing the DNA concentration in the aqueous solution. The synthesized AuNP-DNA conjugates are forced to be encapsulated into double-walled carbon nanotubes (DWNTs) by superimposing a positive DC voltage on the pulse voltage. The AuNP-DNA-conjugate encapsulated DWNTs can be utilized in drug delivery systems when DNA is used as a drug molecule.

AB - Size-controlled gold nanoparticles (AuNPs) covered with DNA are synthesized by using a pulsedriven gas-liquid interfacial discharge plasma (GLIDP) to reduce an aqueous solution of chloroauric acid trihydrate with DNA. The size and the assembly of the AuNPs are found to be easily controlled by changing the DNA concentration in the aqueous solution. The synthesized AuNP-DNA conjugates are forced to be encapsulated into double-walled carbon nanotubes (DWNTs) by superimposing a positive DC voltage on the pulse voltage. The AuNP-DNA-conjugate encapsulated DWNTs can be utilized in drug delivery systems when DNA is used as a drug molecule.

KW - DNA

KW - Drug delivery system

KW - Gas-liquid interfacial discharge plasma

KW - Gold nanoparticle

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ER -

Synthesis of nano-bio conjugates for drug delivery systems using gas-liquid interfacial discharge plasmas

Abstract

Keywords

ASJC Scopus subject areas

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