Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria

Jun Lu; Osamu Yoshida; Sayaka Hayashi; Hirokazu Arimoto

doi:10.1039/b613319c

Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria

Jun Lu, Osamu Yoshida, Sayaka Hayashi, Hirokazu Arimoto

LIF - Molecular and Chemical Life Science

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

A novel and efficient avenue for the preparation of dimeric vancomycins is described, and the dimers exhibited excellent antibacterial activities in the murine infection model.

Original language	English
Pages (from-to)	251-253
Number of pages	3
Journal	Chemical Communications
Issue number	3
DOIs	https://doi.org/10.1039/b613319c
Publication status	Published - 2007

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title = "Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria",

abstract = "A novel and efficient avenue for the preparation of dimeric vancomycins is described, and the dimers exhibited excellent antibacterial activities in the murine infection model.",

author = "Jun Lu and Osamu Yoshida and Sayaka Hayashi and Hirokazu Arimoto",

year = "2007",

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AU - Lu, Jun

AU - Yoshida, Osamu

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Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria

Abstract

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