The C1-C14 portion of altohyrtins (spongistatins) was prepared in a convergent manner from 3,4,6-tri-O-acetyl-D-glucal via a chelation-controlled methylation of ketone, dithiane couplings with epoxides, and a thermodynamically-controlled spitoacetalization.
|Number of pages||4|
|Publication status||Published - 1998 May 28|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry