@article{aa1cb45a0e854405841c32e288812a2c,
title = "Synthetic studies on isoschizogamine: Construction of [3.3.1] bicyclic aminal core by using oxidative skeletal rearrangement This article is dedicated to memory of the late Professor Emeritus Keiichiro Fukumoto",
abstract = "The tetracyclic core structure of isoschizogamine containing aminal functionality was constructed by oxidative skeletal rearrangement of a 1,2-diaminoethene derivative. The 1,2-diaminoethane was prepared by palladium-catalyzed allylation at the 4a position of a 1,2,3,4-tetrahydro- β-carboline derivative and subsequent lactam formation. After the oxidative skeletal rearrangement using dimethyldioxirane, the allyl group was removed by a three-step sequence to provide the tetracyclic core skeleton of isoschizogamine with aminal functionality.",
keywords = "Alkaloid, Allylation, Aminal, Oxidation, Rearrangement",
author = "Hirofumi Ueda and Akihiro Takada and Hidetoshi Tokuyama",
note = "Funding Information: This work was financially supported by the Cabinet Office, Government of Japan through its {\textquoteleft}Funding Program for Next Generation World-Leading Researchers{\textquoteright} ( LS008 ), a Grant-in aid for Young Scientists (B) ( 24790003 ) (for H.U.), An Emergency Fund from Astellas Foundation for Research on Metabolic Disorders to support researchers suffered from 3.11 earthquake and Tsunami, and Tohoku University G-COE program {\textquoteleft}IREMC{\textquoteright}. ",
year = "2013",
month = dec,
day = "25",
doi = "10.1016/j.tetlet.2013.10.083",
language = "English",
volume = "54",
pages = "7115--7118",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd.",
number = "52",
}