TY - JOUR
T1 - Synthetic study towards azadirachtin
T2 - An efficient and stereoselective construction of the AB rings with full functionality
AU - Watanabe, Hidenori
AU - Mori, Naoki
AU - Itoh, Daisuke
AU - Kitahara, Takeshi
AU - Mori, Kenji
PY - 2007
Y1 - 2007
N2 - (Chemical Equation Presented) From A to B: The decalin moiety of azadirachtin, which includes the fully functionalized AB ring system (see picture), was synthesized stereoselectively in only 23 steps. Key steps include an intramolecular Diels-Alder reaction, a decarboxylation, a Claisen rearrangement, and finally a tandem radical cyclization.
AB - (Chemical Equation Presented) From A to B: The decalin moiety of azadirachtin, which includes the fully functionalized AB ring system (see picture), was synthesized stereoselectively in only 23 steps. Key steps include an intramolecular Diels-Alder reaction, a decarboxylation, a Claisen rearrangement, and finally a tandem radical cyclization.
KW - Claisen rearrangement
KW - Diels-Alder reaction
KW - Natural products
KW - Radical reactions
UR - http://www.scopus.com/inward/record.url?scp=34247873121&partnerID=8YFLogxK
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U2 - 10.1002/anie.200604097
DO - 10.1002/anie.200604097
M3 - Article
C2 - 17226885
AN - SCOPUS:34247873121
SN - 1433-7851
VL - 46
SP - 1512
EP - 1516
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 9
ER -