Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany

Mari Yotsu-Yamashita; Dietrich Mebs; Axel Kwet; Michael Schneider

doi:10.1016/j.toxicon.2007.03.019

Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany

Mari Yotsu-Yamashita, Dietrich Mebs, Axel Kwet, Michael Schneider

AGR - Agricultural Chemistry

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

Tetrodotoxin (TTX) and its analogue 6-epitetrodotoxin (6-epiTTX) were quantitatively assayed in 59 newts representing four Triturus species (Triturus alpestris, Triturus cristatus, Triturus helveticus, Triturus vulgaris) from southern Germany by a post-column fluorescent-HPLC system. Both toxins were detected in only 15 specimens of the four species. The toxins levels varied considerably among individuals (TTX: 0.11-9.0 μg/g; 6-epiTTX: 0.05-17.0 μg/g). 6-epiTTX was found to be the major component.

Original language	English
Pages (from-to)	306-309
Number of pages	4
Journal	Toxicon
Volume	50
Issue number	2
DOIs	https://doi.org/10.1016/j.toxicon.2007.03.019
Publication status	Published - 2007 Aug

Keywords

6-epitetrodotoxin
Newts
Tetrodotoxin
Triturus species

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10.1016/j.toxicon.2007.03.019

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title = "Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany",

abstract = "Tetrodotoxin (TTX) and its analogue 6-epitetrodotoxin (6-epiTTX) were quantitatively assayed in 59 newts representing four Triturus species (Triturus alpestris, Triturus cristatus, Triturus helveticus, Triturus vulgaris) from southern Germany by a post-column fluorescent-HPLC system. Both toxins were detected in only 15 specimens of the four species. The toxins levels varied considerably among individuals (TTX: 0.11-9.0 μg/g; 6-epiTTX: 0.05-17.0 μg/g). 6-epiTTX was found to be the major component.",

keywords = "6-epitetrodotoxin, Newts, Tetrodotoxin, Triturus species",

author = "Mari Yotsu-Yamashita and Dietrich Mebs and Axel Kwet and Michael Schneider",

note = "Funding Information: We are grateful to Dr. Andreas Schl{\"u}ter and Mr. Markus-Julius Trepte for assistance in collecting newts, and Mr. Y. Otomo, Tohoku University, for assistance in HPLC analysis. This work was supported by Nagase Science and Technology Foundation, and by Grants-in-Aid for Scientific Research on Priority Areas from MEXT (18032014), and from JSPS (17580091) to M.Y.Y.",

year = "2007",

month = aug,

doi = "10.1016/j.toxicon.2007.03.019",

language = "English",

volume = "50",

pages = "306--309",

journal = "Toxicon",

issn = "0041-0101",

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T1 - Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany

AU - Yotsu-Yamashita, Mari

AU - Mebs, Dietrich

AU - Kwet, Axel

AU - Schneider, Michael

N1 - Funding Information: We are grateful to Dr. Andreas Schlüter and Mr. Markus-Julius Trepte for assistance in collecting newts, and Mr. Y. Otomo, Tohoku University, for assistance in HPLC analysis. This work was supported by Nagase Science and Technology Foundation, and by Grants-in-Aid for Scientific Research on Priority Areas from MEXT (18032014), and from JSPS (17580091) to M.Y.Y.

PY - 2007/8

Y1 - 2007/8

N2 - Tetrodotoxin (TTX) and its analogue 6-epitetrodotoxin (6-epiTTX) were quantitatively assayed in 59 newts representing four Triturus species (Triturus alpestris, Triturus cristatus, Triturus helveticus, Triturus vulgaris) from southern Germany by a post-column fluorescent-HPLC system. Both toxins were detected in only 15 specimens of the four species. The toxins levels varied considerably among individuals (TTX: 0.11-9.0 μg/g; 6-epiTTX: 0.05-17.0 μg/g). 6-epiTTX was found to be the major component.

AB - Tetrodotoxin (TTX) and its analogue 6-epitetrodotoxin (6-epiTTX) were quantitatively assayed in 59 newts representing four Triturus species (Triturus alpestris, Triturus cristatus, Triturus helveticus, Triturus vulgaris) from southern Germany by a post-column fluorescent-HPLC system. Both toxins were detected in only 15 specimens of the four species. The toxins levels varied considerably among individuals (TTX: 0.11-9.0 μg/g; 6-epiTTX: 0.05-17.0 μg/g). 6-epiTTX was found to be the major component.

KW - 6-epitetrodotoxin

KW - Newts

KW - Tetrodotoxin

KW - Triturus species

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SN - 0041-0101

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JO - Toxicon

JF - Toxicon

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ER -

Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany

Abstract

Keywords

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