The accumulation of11C-methionine in cerebral glioma patients studied with PET

M. Kameyama; R. Shirane; J. Itoh; K. Sato; R. Katakura; T. Yoshimoto; J. Hatazawa; M. Itoh; T. Ido

doi:10.1007/BF01842885

The accumulation of¹¹C-methionine in cerebral glioma patients studied with PET

M. Kameyama, R. Shirane, J. Itoh, K. Sato, R. Katakura, T. Yoshimoto, J. Hatazawa, M. Itoh, T. Ido

Cyclotron and Radioisotope Center (CYRIC)

Tohoku University

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

Fourteen patients with cerebral gliomas were studied with positron emission tomography (PET) using L-[methyl-¹¹C]methionine (¹¹C-MET). Positive images of tumour were obtained in all cases regardless of histological grades. The analysis of differential absorption ratio (DAR) showed the higher accumulation of¹¹C-MET in high grade gliomas than in low grade gliomas. PET study with¹¹C-MET will be of great value not only in delineating the location of gliomas, but also in making a qualitative diagnosis from the view point of the biological properties of gliomas.

Original language	English
Pages (from-to)	8-12
Number of pages	5
Journal	Acta Neurochirurgica
Volume	104
Issue number	1-2
DOIs	https://doi.org/10.1007/BF01842885
Publication status	Published - 1990 Mar

Keywords

C-methionine
Amino acid metabolism
brain tumour
cerebral glioma
PET

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10.1007/BF01842885

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abstract = "Fourteen patients with cerebral gliomas were studied with positron emission tomography (PET) using L-[methyl-11C]methionine (11C-MET). Positive images of tumour were obtained in all cases regardless of histological grades. The analysis of differential absorption ratio (DAR) showed the higher accumulation of11C-MET in high grade gliomas than in low grade gliomas. PET study with11C-MET will be of great value not only in delineating the location of gliomas, but also in making a qualitative diagnosis from the view point of the biological properties of gliomas.",

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AU - Kameyama, M.

AU - Shirane, R.

AU - Itoh, J.

AU - Sato, K.

AU - Katakura, R.

AU - Yoshimoto, T.

AU - Hatazawa, J.

AU - Itoh, M.

AU - Ido, T.

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The accumulation of¹¹C-methionine in cerebral glioma patients studied with PET

Abstract

Keywords

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