The bioactivity of PDMS-CaO-SiO2 based hybrid materials prepared by the addition of transition metal alkoxides

Manabu Fukushima, Eiichi Yasuda, Hideki Kita, Masao Shimizu, Yasuto Hoshikawa, Yasuhiro Tanabe

Research output: Contribution to journalConference articlepeer-review

2 Citations (Scopus)


The bioactivity of organic inorganic hybrid materials derived from polydimethylsiloxane, tetraethoxysilane, calcium nitrate tetrahydrate and a different amount of pentaethoxy-niobium/tantalum was examined. We investigated the relationship between the hydroxyapatite depositions on the hybrid's surface in a simulated body fluid (KOKUBO solution) and the molecular structure oh hybrids. The in vitro formation of hydroxyapatite was characterized by using a simulated body fluid and the molecular structure of the hybrid was characterized by fourier transformed infrared and silicon 29 solid-state magic angle spinning nuclear magnetic resonance. The addition of a different amount of transition metal alkoxides lead to a different amount of silanol in the obtained hybrid materials. Additionally, the releasing ability of calcium from hybrid into simulated body fluid was different among the obtained hybrid materials, corresponding to the amount of transition metal. The hybrid material with a ratio of 0/1 and 1/0=Nb/Ta, polydimethylsiloxane/tetraethoxysilane=0.1/1 and 0.1=(Ta+Nb)/tetraethoxysilane showed the higher apatite formation ability.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalCeramic Engineering and Science Proceedings
Issue number6
Publication statusPublished - 2005 Dec 1
Externally publishedYes
Event29th International Conference on Advanced Ceramics and Composites - Cocoa Beach, FL, United States
Duration: 2005 Jan 232005 Jan 28

ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry


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