Abstract
A chiral diamine, easily prepared from proline, is an effective, asymmetric organic catalyst for the Baylis-Hillman reaction of aldehydes and methyl vinyl ketone, affording adducts with enantio-selectivities up to 75%.
| Original language | English |
|---|---|
| Pages (from-to) | 1106-1110 |
| Number of pages | 5 |
| Journal | Advanced Synthesis and Catalysis |
| Volume | 346 |
| Issue number | 9-10 |
| DOIs | |
| Publication status | Published - 2004 Aug |
| Externally published | Yes |
Keywords
- Asymmetric synthesis
- Baylis-Hillman reaction
- Diamines
- Enones
- Lewis base catalysts
- Organic catalysis
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry