TY - JOUR
T1 - The distribution and origin of substance P-like immunoreactivity in the rat molar pulp and periodontal tissues
AU - Wakisaka, S.
AU - Nishikawa, S.
AU - Ichikawa, H.
AU - Matsuo, S.
AU - Takano, Y.
AU - Akai, M.
N1 - Funding Information:
Acknowledgement-Thiss tudy was partly supportedb y a grant (No. 60771450i)n aid for FundamentalS cientific Researchf rom the JapaneseM inistry of Education.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1985
Y1 - 1985
N2 - Rat mandibles were fixed in Zamboni fixative and demineralized in a mixture of EDTA and fixative. Substance P-like immunoreactivity was demonstrated by indirect immunofluorescence in molar pulp, periodontal ligament and gingiva. Substance P (SP) containing nerve fibres with varicosities were observed in the pulp horn and root pulp in general located around blood vessels. Some SP-containing fibres penetrated into the predentine and dentine. In the periodontal ligament, SP fibres were localized along the blood vessels in the middle and apical regions. Many SP-containing fibres were associated with the blood vessels in the lamina propria of gingiva. After inferior alveolar nerve section, SP-positive nerve fibres in the pulp and periodontal ligament disappeared completely. In gingiva the number of SP fibres decreased but not all fibres disappeared. Removal of the superior cervical ganglion did not affect the distribution of SP-containing nerve fibres.
AB - Rat mandibles were fixed in Zamboni fixative and demineralized in a mixture of EDTA and fixative. Substance P-like immunoreactivity was demonstrated by indirect immunofluorescence in molar pulp, periodontal ligament and gingiva. Substance P (SP) containing nerve fibres with varicosities were observed in the pulp horn and root pulp in general located around blood vessels. Some SP-containing fibres penetrated into the predentine and dentine. In the periodontal ligament, SP fibres were localized along the blood vessels in the middle and apical regions. Many SP-containing fibres were associated with the blood vessels in the lamina propria of gingiva. After inferior alveolar nerve section, SP-positive nerve fibres in the pulp and periodontal ligament disappeared completely. In gingiva the number of SP fibres decreased but not all fibres disappeared. Removal of the superior cervical ganglion did not affect the distribution of SP-containing nerve fibres.
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U2 - 10.1016/0003-9969(85)90136-0
DO - 10.1016/0003-9969(85)90136-0
M3 - Article
C2 - 2421695
AN - SCOPUS:0022325968
SN - 0003-9969
VL - 30
SP - 813
EP - 818
JO - Archives of Oral Biology
JF - Archives of Oral Biology
IS - 11-12
ER -