TY - JOUR
T1 - The My Active and Healthy Aging (My-AHA) ICT platform to detect and prevent frailty in older adults
T2 - Randomized control trial design and protocol
AU - My-AHA Consortium
AU - Summers, Mathew J.
AU - Rainero, Innocenzo
AU - Vercelli, Alessandro E.
AU - Aumayr, Georg
AU - de Rosario, Helios
AU - Mönter, Michaela
AU - Kawashima, Ryuta
AU - Caglio, M.
AU - Carbone, C.
AU - Rubino, E.
AU - Sousa, I.
AU - Vasconcelos, M. J.M.
AU - Madureira, P.
AU - Ribeiro, J.
AU - Cardoso, N.
AU - Giannouli, E.
AU - Zijlstra, W.
AU - Alonso, S.
AU - Schnieder, S.
AU - Roelen, S. D.
AU - Kächele, L.
AU - Krajewski, J.
AU - Laparra, J.
AU - Serrano, J. F.
AU - Medina, E.
AU - López, A.
AU - Pedrero, J. F.
AU - Martínez,
AU - Bazzani, M.
AU - Cogerino, C.
AU - Toso, G. M.
AU - Tommasone, G.
AU - Frisello, A.
AU - Haider, G.
AU - Bleier, D.
AU - Sturm, N.
AU - Kaartinen, N.
AU - Kern, A.
AU - Bandelow, S.
AU - Niederstrasser, N. G.
AU - Vaziri, D.
AU - Tabatabaei, A.
AU - Gouverneur, P.
AU - Lagodzinski, P.
AU - Wieching, R.
AU - Grzegorek, M.
AU - Shariat Yazdi, H.
AU - Shirahama, K.
AU - Wulf, V.
AU - Nouchi, R.
N1 - Funding Information:
This project has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 689582 and the Australian National Health and Medical Research Council (NHRMC) European Union grant scheme (1115818). M.J.S. reports personal fees from Eli Lilly (Australia) Pty Ltd and grants from Novotech Pty Ltd, outside the submitted work. All other authors report nothing to disclose.
Publisher Copyright:
© 2018 The Authors
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Introduction: Frailty increases the risk of poor health outcomes, disability, hospitalization, and death in older adults and affects 7%–12% of the aging population. Secondary impacts of frailty on psychological health and socialization are significant negative contributors to poor outcomes for frail older adults. Method: The My Active and Healthy Aging (My-AHA) consortium has developed an information and communications technology–based platform to support active and healthy aging through early detection of prefrailty and provision of individually tailored interventions, targeting multidomain risks for frailty across physical activity, cognitive activity, diet and nutrition, sleep, and psychosocial activities. Six hundred adults aged 60 years and older will be recruited to participate in a multinational, multisite 18-month randomized controlled trial to test the efficacy of the My-AHA platform to detect prefrailty and the efficacy of individually tailored interventions to prevent development of clinical frailty in this cohort. A total of 10 centers from Italy, Germany, Austria, Spain, United Kingdom, Belgium, Sweden, Japan, South Korea, and Australia will participate in the randomized controlled trial. Results: Pilot testing (Alpha Wave) of the My-AHA platform and all ancillary systems has been completed with a small group of older adults in Europe with the full randomized controlled trial scheduled to commence in 2018. Discussion: The My-AHA study will expand the understanding of antecedent risk factors for clinical frailty so as to deliver targeted interventions to adults with prefrailty. Through the use of an information and communications technology platform that can connect with multiple devices within the older adult's own home, the My-AHA platform is designed to measure an individual's risk factors for frailty across multiple domains and then deliver personalized domain-specific interventions to the individual. The My-AHA platform is technology-agnostic, enabling the integration of new devices and sensor platforms as they emerge.
AB - Introduction: Frailty increases the risk of poor health outcomes, disability, hospitalization, and death in older adults and affects 7%–12% of the aging population. Secondary impacts of frailty on psychological health and socialization are significant negative contributors to poor outcomes for frail older adults. Method: The My Active and Healthy Aging (My-AHA) consortium has developed an information and communications technology–based platform to support active and healthy aging through early detection of prefrailty and provision of individually tailored interventions, targeting multidomain risks for frailty across physical activity, cognitive activity, diet and nutrition, sleep, and psychosocial activities. Six hundred adults aged 60 years and older will be recruited to participate in a multinational, multisite 18-month randomized controlled trial to test the efficacy of the My-AHA platform to detect prefrailty and the efficacy of individually tailored interventions to prevent development of clinical frailty in this cohort. A total of 10 centers from Italy, Germany, Austria, Spain, United Kingdom, Belgium, Sweden, Japan, South Korea, and Australia will participate in the randomized controlled trial. Results: Pilot testing (Alpha Wave) of the My-AHA platform and all ancillary systems has been completed with a small group of older adults in Europe with the full randomized controlled trial scheduled to commence in 2018. Discussion: The My-AHA study will expand the understanding of antecedent risk factors for clinical frailty so as to deliver targeted interventions to adults with prefrailty. Through the use of an information and communications technology platform that can connect with multiple devices within the older adult's own home, the My-AHA platform is designed to measure an individual's risk factors for frailty across multiple domains and then deliver personalized domain-specific interventions to the individual. The My-AHA platform is technology-agnostic, enabling the integration of new devices and sensor platforms as they emerge.
KW - Cognition
KW - Frailty
KW - Mood
KW - Nutrition
KW - Older adults
KW - Physical activity
KW - Randomized control trial
KW - Social activity
UR - http://www.scopus.com/inward/record.url?scp=85050107386&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85050107386&partnerID=8YFLogxK
U2 - 10.1016/j.trci.2018.06.004
DO - 10.1016/j.trci.2018.06.004
M3 - Article
AN - SCOPUS:85050107386
SN - 2352-8737
VL - 4
SP - 252
EP - 262
JO - Alzheimer's and Dementia: Translational Research and Clinical Interventions
JF - Alzheimer's and Dementia: Translational Research and Clinical Interventions
ER -
