The neural correlates of driving performance identified using positron emission tomography

Etsuo Horikawa; Nobuyuki Okamura; Manabu Tashiro; Yumiko Sakurada; Masahiro Maruyama; Hiroyuki Arai; Keiichiro Yamaguchi; Hidetada Sasaki; Kazuhiko Yanai; Masatoshi Itoh

doi:10.1016/j.bandc.2004.10.002

The neural correlates of driving performance identified using positron emission tomography

Etsuo Horikawa, Nobuyuki Okamura, Manabu Tashiro, Yumiko Sakurada, Masahiro Maruyama, Hiroyuki Arai, Keiichiro Yamaguchi, Hidetada Sasaki, Kazuhiko Yanai, Masatoshi Itoh

Cyclotron and Radioisotope Center (CYRIC)

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Driving is a complex behavior involving multiple cognitive domains. To identify neural correlates of driving performance, [¹⁵O]H ₂O positron emission tomography was performed using a simulated driving task. Compared with the resting condition, simulated driving increased regional cerebral blood flow (rCBF) in the cerebellum, occipital, and parietal cortices. Correlations between rCBF and measurements of driving performance were evaluated during simulated driving. Interestingly, rCBF in the thalamus, midbrain, and cerebellum were positively correlated with time required to complete the course and rCBF in the posterior cingulate gyrus was positively correlated with number of crashes during the task. These brain regions may thus play roles in the maintenance of driving performance.

Original language	English
Pages (from-to)	166-171
Number of pages	6
Journal	Brain and Cognition
Volume	58
Issue number	2
DOIs	https://doi.org/10.1016/j.bandc.2004.10.002
Publication status	Published - 2005 Jul

Keywords

Cerebral blood flow
Cingulate gyrus
Driving
Midbrain
Performance
Positron emission tomography
Thalamus

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10.1016/j.bandc.2004.10.002

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title = "The neural correlates of driving performance identified using positron emission tomography",

abstract = "Driving is a complex behavior involving multiple cognitive domains. To identify neural correlates of driving performance, [15O]H 2O positron emission tomography was performed using a simulated driving task. Compared with the resting condition, simulated driving increased regional cerebral blood flow (rCBF) in the cerebellum, occipital, and parietal cortices. Correlations between rCBF and measurements of driving performance were evaluated during simulated driving. Interestingly, rCBF in the thalamus, midbrain, and cerebellum were positively correlated with time required to complete the course and rCBF in the posterior cingulate gyrus was positively correlated with number of crashes during the task. These brain regions may thus play roles in the maintenance of driving performance.",

keywords = "Cerebral blood flow, Cingulate gyrus, Driving, Midbrain, Performance, Positron emission tomography, Thalamus",

author = "Etsuo Horikawa and Nobuyuki Okamura and Manabu Tashiro and Yumiko Sakurada and Masahiro Maruyama and Hiroyuki Arai and Keiichiro Yamaguchi and Hidetada Sasaki and Kazuhiko Yanai and Masatoshi Itoh",

note = "Funding Information: This research was partly supported by a grant from the TOYOTA Advanced Technology Support Program. ",

year = "2005",

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doi = "10.1016/j.bandc.2004.10.002",

language = "English",

volume = "58",

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T1 - The neural correlates of driving performance identified using positron emission tomography

AU - Horikawa, Etsuo

AU - Okamura, Nobuyuki

AU - Tashiro, Manabu

AU - Sakurada, Yumiko

AU - Maruyama, Masahiro

AU - Arai, Hiroyuki

AU - Yamaguchi, Keiichiro

AU - Sasaki, Hidetada

AU - Yanai, Kazuhiko

AU - Itoh, Masatoshi

N1 - Funding Information: This research was partly supported by a grant from the TOYOTA Advanced Technology Support Program.

PY - 2005/7

Y1 - 2005/7

N2 - Driving is a complex behavior involving multiple cognitive domains. To identify neural correlates of driving performance, [15O]H 2O positron emission tomography was performed using a simulated driving task. Compared with the resting condition, simulated driving increased regional cerebral blood flow (rCBF) in the cerebellum, occipital, and parietal cortices. Correlations between rCBF and measurements of driving performance were evaluated during simulated driving. Interestingly, rCBF in the thalamus, midbrain, and cerebellum were positively correlated with time required to complete the course and rCBF in the posterior cingulate gyrus was positively correlated with number of crashes during the task. These brain regions may thus play roles in the maintenance of driving performance.

AB - Driving is a complex behavior involving multiple cognitive domains. To identify neural correlates of driving performance, [15O]H 2O positron emission tomography was performed using a simulated driving task. Compared with the resting condition, simulated driving increased regional cerebral blood flow (rCBF) in the cerebellum, occipital, and parietal cortices. Correlations between rCBF and measurements of driving performance were evaluated during simulated driving. Interestingly, rCBF in the thalamus, midbrain, and cerebellum were positively correlated with time required to complete the course and rCBF in the posterior cingulate gyrus was positively correlated with number of crashes during the task. These brain regions may thus play roles in the maintenance of driving performance.

KW - Cerebral blood flow

KW - Cingulate gyrus

KW - Driving

KW - Midbrain

KW - Performance

KW - Positron emission tomography

KW - Thalamus

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VL - 58

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JO - Brain and Cognition

JF - Brain and Cognition

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ER -

The neural correlates of driving performance identified using positron emission tomography

Abstract

Keywords

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