The one-step preparation of sugar oxazoline enables the synthesis of glycoprotein having a definite structure

Masato Noguchi; Atsushi Kobayashi; Shin Ichiro Shoda

doi:10.4052/tigg.1505.2E

The one-step preparation of sugar oxazoline enables the synthesis of glycoprotein having a definite structure

Masato Noguchi, Atsushi Kobayashi, Shin Ichiro Shoda

ENG - Biomolecular Engineering

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Sugar oxazoline derivatives are useful donor substrates for N-acetylglucosaminidase-catalyzed glycosylation reactions. In this review, we describe the direct conversion of free sugars to their oxazoline derivatives by using water-soluble dehydrating agents and its application to enzymatic synthesis of complex glycosidic compounds including glycoproteins.

Original language	English
Pages (from-to)	E35-E42
Journal	Trends in Glycoscience and Glycotechnology
Volume	27
Issue number	158
DOIs	https://doi.org/10.4052/tigg.1505.2E
Publication status	Published - 2015 Nov 25

Keywords

Dehydrating agent
Endo-N-acetyl glucosaminidase
Glycoprotein
Sugar oxazoline

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

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10.4052/tigg.1505.2E

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title = "The one-step preparation of sugar oxazoline enables the synthesis of glycoprotein having a definite structure",

abstract = "Sugar oxazoline derivatives are useful donor substrates for N-acetylglucosaminidase-catalyzed glycosylation reactions. In this review, we describe the direct conversion of free sugars to their oxazoline derivatives by using water-soluble dehydrating agents and its application to enzymatic synthesis of complex glycosidic compounds including glycoproteins.",

keywords = "Dehydrating agent, Endo-N-acetyl glucosaminidase, Glycoprotein, Sugar oxazoline",

author = "Masato Noguchi and Atsushi Kobayashi and Shoda, {Shin Ichiro}",

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AU - Noguchi, Masato

AU - Kobayashi, Atsushi

AU - Shoda, Shin Ichiro

PY - 2015/11/25

Y1 - 2015/11/25

N2 - Sugar oxazoline derivatives are useful donor substrates for N-acetylglucosaminidase-catalyzed glycosylation reactions. In this review, we describe the direct conversion of free sugars to their oxazoline derivatives by using water-soluble dehydrating agents and its application to enzymatic synthesis of complex glycosidic compounds including glycoproteins.

AB - Sugar oxazoline derivatives are useful donor substrates for N-acetylglucosaminidase-catalyzed glycosylation reactions. In this review, we describe the direct conversion of free sugars to their oxazoline derivatives by using water-soluble dehydrating agents and its application to enzymatic synthesis of complex glycosidic compounds including glycoproteins.

KW - Dehydrating agent

KW - Endo-N-acetyl glucosaminidase

KW - Glycoprotein

KW - Sugar oxazoline

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JF - Trends in Glycoscience and Glycotechnology

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ER -

The one-step preparation of sugar oxazoline enables the synthesis of glycoprotein having a definite structure

Abstract

Keywords

ASJC Scopus subject areas

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