The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian community

Kaori Ohmori; Satoru Ebihara; Shinichi Kuriyama; Takashi Ugajin; Mikiko Ogata; Atsushi Hozawa; Toshifumi Matsui; Yoshitaka Tsubono; Hiroyuki Arai; Hidetada Sasaki; Ichiro Tsuji

doi:10.1016/j.annepidem.2004.04.001

The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian community

Kaori Ohmori, Satoru Ebihara, Shinichi Kuriyama, Takashi Ugajin, Mikiko Ogata, Atsushi Hozawa, Toshifumi Matsui, Yoshitaka Tsubono, Hiroyuki Arai, Hidetada Sasaki, Ichiro Tsuji

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

To examine the association between body mass index (BMI) and the plasma level of a lipid peroxidation biomarker in a large sample of elderly healthy Asian population. This cross-sectional study included 1150 community-dwelling Japanese aged 70 years or older in 2002. We measured the lipid peroxidation biomarker 8-iso-prostaglandin F _2α (8-iso-PGF _2α) using the ELISA method. We also measured the weight and height and calculated the BMI as weight (kg)/height (m) ². After adjustment for potential confounders, the mean ± SE plasma 8-iso-PGF _2α level was significantly higher in subjects with higher BMI: 21.1 ± 0.8 pg/ml in those with BMI of 30.0 or more; 20.5 ± 0.3 pg/ml in those with BMI between 25.0 and 29.9; 20.0 ± 0.2 pg/ml in those with BMI between 18.5 and 24.9; and 19.0 ± 0.7 pg/ml in those with BMI of less than 18.5 (p for trend = 0.011). Our results demonstrated that in the healthy Asian population, there was a modest but significant relationship between BMI and the plasma lipid peroxidation level.

Original language	English
Pages (from-to)	80-84
Number of pages	5
Journal	Annals of Epidemiology
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.annepidem.2004.04.001
Publication status	Published - 2005 Jan
Externally published	Yes

Keywords

Aged
Asia
Body Mass Index
Isoprostanes
Obesity
Oxidative Stress

ASJC Scopus subject areas

Epidemiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.annepidem.2004.04.001

Cite this

@article{fd4eb1a5ad1344e2a9382ddd5fc03b3d,

title = "The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian community",

abstract = "To examine the association between body mass index (BMI) and the plasma level of a lipid peroxidation biomarker in a large sample of elderly healthy Asian population. This cross-sectional study included 1150 community-dwelling Japanese aged 70 years or older in 2002. We measured the lipid peroxidation biomarker 8-iso-prostaglandin F 2α (8-iso-PGF 2α) using the ELISA method. We also measured the weight and height and calculated the BMI as weight (kg)/height (m) 2. After adjustment for potential confounders, the mean ± SE plasma 8-iso-PGF 2α level was significantly higher in subjects with higher BMI: 21.1 ± 0.8 pg/ml in those with BMI of 30.0 or more; 20.5 ± 0.3 pg/ml in those with BMI between 25.0 and 29.9; 20.0 ± 0.2 pg/ml in those with BMI between 18.5 and 24.9; and 19.0 ± 0.7 pg/ml in those with BMI of less than 18.5 (p for trend = 0.011). Our results demonstrated that in the healthy Asian population, there was a modest but significant relationship between BMI and the plasma lipid peroxidation level.",

keywords = "Aged, Asia, Body Mass Index, Isoprostanes, Obesity, Oxidative Stress",

author = "Kaori Ohmori and Satoru Ebihara and Shinichi Kuriyama and Takashi Ugajin and Mikiko Ogata and Atsushi Hozawa and Toshifumi Matsui and Yoshitaka Tsubono and Hiroyuki Arai and Hidetada Sasaki and Ichiro Tsuji",

note = "Funding Information: This study was supported by Grants for Scientific Research (13557031) and for JSPS's Research (1410301) from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and by a Research Grant (2002) from the Japan Atherosclerosis Prevention Fund, and by a Health Science Grant on Health Services (H13-kenko-008) and by a Comprehensive Research on Aging and Health (H13-choju-007, H13-choju-023) grant from the Ministry of Health, Labour, and Welfare of Japan. ",

year = "2005",

month = jan,

doi = "10.1016/j.annepidem.2004.04.001",

language = "English",

volume = "15",

pages = "80--84",

journal = "Annals of Epidemiology",

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T1 - The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian community

AU - Ohmori, Kaori

AU - Ebihara, Satoru

AU - Kuriyama, Shinichi

AU - Ugajin, Takashi

AU - Ogata, Mikiko

AU - Hozawa, Atsushi

AU - Matsui, Toshifumi

AU - Tsubono, Yoshitaka

AU - Arai, Hiroyuki

AU - Sasaki, Hidetada

AU - Tsuji, Ichiro

N1 - Funding Information: This study was supported by Grants for Scientific Research (13557031) and for JSPS's Research (1410301) from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and by a Research Grant (2002) from the Japan Atherosclerosis Prevention Fund, and by a Health Science Grant on Health Services (H13-kenko-008) and by a Comprehensive Research on Aging and Health (H13-choju-007, H13-choju-023) grant from the Ministry of Health, Labour, and Welfare of Japan.

PY - 2005/1

Y1 - 2005/1

N2 - To examine the association between body mass index (BMI) and the plasma level of a lipid peroxidation biomarker in a large sample of elderly healthy Asian population. This cross-sectional study included 1150 community-dwelling Japanese aged 70 years or older in 2002. We measured the lipid peroxidation biomarker 8-iso-prostaglandin F 2α (8-iso-PGF 2α) using the ELISA method. We also measured the weight and height and calculated the BMI as weight (kg)/height (m) 2. After adjustment for potential confounders, the mean ± SE plasma 8-iso-PGF 2α level was significantly higher in subjects with higher BMI: 21.1 ± 0.8 pg/ml in those with BMI of 30.0 or more; 20.5 ± 0.3 pg/ml in those with BMI between 25.0 and 29.9; 20.0 ± 0.2 pg/ml in those with BMI between 18.5 and 24.9; and 19.0 ± 0.7 pg/ml in those with BMI of less than 18.5 (p for trend = 0.011). Our results demonstrated that in the healthy Asian population, there was a modest but significant relationship between BMI and the plasma lipid peroxidation level.

AB - To examine the association between body mass index (BMI) and the plasma level of a lipid peroxidation biomarker in a large sample of elderly healthy Asian population. This cross-sectional study included 1150 community-dwelling Japanese aged 70 years or older in 2002. We measured the lipid peroxidation biomarker 8-iso-prostaglandin F 2α (8-iso-PGF 2α) using the ELISA method. We also measured the weight and height and calculated the BMI as weight (kg)/height (m) 2. After adjustment for potential confounders, the mean ± SE plasma 8-iso-PGF 2α level was significantly higher in subjects with higher BMI: 21.1 ± 0.8 pg/ml in those with BMI of 30.0 or more; 20.5 ± 0.3 pg/ml in those with BMI between 25.0 and 29.9; 20.0 ± 0.2 pg/ml in those with BMI between 18.5 and 24.9; and 19.0 ± 0.7 pg/ml in those with BMI of less than 18.5 (p for trend = 0.011). Our results demonstrated that in the healthy Asian population, there was a modest but significant relationship between BMI and the plasma lipid peroxidation level.

KW - Aged

KW - Asia

KW - Body Mass Index

KW - Isoprostanes

KW - Obesity

KW - Oxidative Stress

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SN - 1047-2797

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JO - Annals of Epidemiology

JF - Annals of Epidemiology

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ER -

The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian community

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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