TY - JOUR
T1 - The use of tacrolimus for recurrent lupus enteritis
T2 - A case report
AU - Shirai, Tsuyoshi
AU - Hirabayashi, Yasuhiko
AU - Watanabe, Ryu
AU - Tajima, Yumi
AU - Fujii, Hiroshi
AU - Takasawa, Naruhiko
AU - Ishii, Tomonori
AU - Harigae, Hideo
PY - 2010
Y1 - 2010
N2 - Introduction. Patients with lupus enteritis sometimes experience recurrence. In such cases, the addition of cyclophosphamide to the treatment regimen is recommended. However, an appropriate treatment has not been established in cases where cyclophosphamide failed to prevent the disease. Case presentation. An 18-year-old Japanese woman was admitted for a recurrence of lupus enteritis. One year before admission she was treated for lupus enteritis with high-dose corticosteroid together with intravenous cyclophosphamide pulse therapy. Upon admission, she was administered again with high-dose corticosteroid and her abdominal pain rapidly subsided. Tacrolimus was later used as an immunosuppressive agent and a complete remission has been maintained. Conclusion. Tacrolimus can be a useful agent for recurrent lupus enteritis that is resistant to conventional therapy.
AB - Introduction. Patients with lupus enteritis sometimes experience recurrence. In such cases, the addition of cyclophosphamide to the treatment regimen is recommended. However, an appropriate treatment has not been established in cases where cyclophosphamide failed to prevent the disease. Case presentation. An 18-year-old Japanese woman was admitted for a recurrence of lupus enteritis. One year before admission she was treated for lupus enteritis with high-dose corticosteroid together with intravenous cyclophosphamide pulse therapy. Upon admission, she was administered again with high-dose corticosteroid and her abdominal pain rapidly subsided. Tacrolimus was later used as an immunosuppressive agent and a complete remission has been maintained. Conclusion. Tacrolimus can be a useful agent for recurrent lupus enteritis that is resistant to conventional therapy.
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U2 - 10.1186/1752-1947-4-150
DO - 10.1186/1752-1947-4-150
M3 - Article
AN - SCOPUS:77953855886
SN - 1752-1947
VL - 4
JO - Journal of Medical Case Reports
JF - Journal of Medical Case Reports
M1 - 150
ER -