Theoretical study and simulation of light-addressable potentiometric sensors

Yuanyuan Guo, Ko Ichiro Miyamoto, Torsten Wagner, Michael J. Schöning, Tatsuo Yoshinobu

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance. Distribution of minority carriers inside a Si-based LAPS structure under illumination with different wavelengths.

Original languageEnglish
Pages (from-to)1467-1472
Number of pages6
JournalPhysica Status Solidi (A) Applications and Materials Science
Issue number6
Publication statusPublished - 2014 Jun


  • biosensors
  • device simulations
  • light-addressable potentiometric sensors


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