TY - JOUR
T1 - Therapeutic efficacy of lanoconazole, a new imidazole antimycotic agent, for experimental cutaneous candidiasis in guinea pigs
AU - Niwano, Y.
AU - Seo, A.
AU - Kanai, K.
AU - Hamaguchi, H.
AU - Uchida, K.
AU - Yamaguchi, H.
PY - 1994
Y1 - 1994
N2 - The therapeutic efficacy of 1% cream and 1% solution of lanoconazole, a new imidazole antimycotic agent, in the model of cutaneous candidiasis in prednisolone-treated guinea pigs was evaluated in comparison with that of comparable formulations of bifonazole. Each preparation was topically applied once a day for 3 consecutive days, starting on the fifth day postinfection, and quantitative culture study was conducted on the ninth day postinfection. Both formulations of lanoconazole were much more highly effective in terms of eradication of fungi than the bifonazole formulations.
AB - The therapeutic efficacy of 1% cream and 1% solution of lanoconazole, a new imidazole antimycotic agent, in the model of cutaneous candidiasis in prednisolone-treated guinea pigs was evaluated in comparison with that of comparable formulations of bifonazole. Each preparation was topically applied once a day for 3 consecutive days, starting on the fifth day postinfection, and quantitative culture study was conducted on the ninth day postinfection. Both formulations of lanoconazole were much more highly effective in terms of eradication of fungi than the bifonazole formulations.
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U2 - 10.1128/AAC.38.9.2204
DO - 10.1128/AAC.38.9.2204
M3 - Comment/debate
C2 - 7811048
AN - SCOPUS:0028088078
SN - 0066-4804
VL - 38
SP - 2204
EP - 2206
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 9
ER -
