Thermal simulation of cavitation-enhanced ultrasonic heating verified with tissue-mimicking gel

Tatsuya Moriyama, Shin Yoshizawa, Shin Ichiro Umemura

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


High-intensity focused ultrasound (HIFU) causes selective tissue necrosis through heating and is used as a noninvasive treatment in cancer therapy. However, there is a problem that it takes several hours to treat a large tumor. To shorten the treatment time, there is need for the development of a highly efficient method. It is known that cavitation bubbles generated by HIFU enhance the heating effect of ultrasound. In this study, the enhancement of the heating effect due to cavitation was considered in the bio-heat transfer equation (BHTE) by increasing the absorption coefficient in the region of generated cavitation. The absorption coefficient was calculated by curve fitting between the temperature rise at the focal point in the experiment and that in the simulation. The results show that the increased absorption can simulate the enhancement of the temperature rise by cavitation bubbles.

Original languageEnglish
Article number07GF27
JournalJapanese journal of applied physics
Issue number7 PART2
Publication statusPublished - 2012 Jul

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)


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