Total synthesis of dictyodendrin A and B

Kentaro Okano, Hideto Fujiwara, Toshiharu Noji, Tohru Fukuyama, Hidetoshi Tokuyama

Research output: Contribution to journalArticlepeer-review

91 Citations (Scopus)


(Figure Presented) In-do-line of fire: A highly efficient total synthesis of the title compounds features a novel benzyne-mediated one-pot indoline formation/cross-coupling sequence for the construction of a highly substituted key indoline intermediate. The peripheral substituents were then introduced onto the intermediate in a modular fashion to complete the total syntheses of dictyodendrin A and B.

Original languageEnglish
Pages (from-to)5925-5929
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number34
Publication statusPublished - 2010 Aug 9


  • Arynes
  • Cross-coupling
  • Cyclization
  • Natural products
  • Total synthesis


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