Total synthesis of (-)-polycavernoside A: Suzuki-Miyaura coupling approach

Yusuke Kasai, Takanori Ito, Makoto Sasaki

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


A total synthesis of (-)-polycavernoside A, a marine lethal toxin isolated from the edible alga Gracilaria edulis, has been achieved via a convergent approach. The synthesis is highlighted by catalytic asymmetric syntheses of the two key fragments and their union through Suzuki-Miyaura coupling and Keck macrolactonization.

Original languageEnglish
Pages (from-to)3186-3189
Number of pages4
JournalOrganic Letters
Issue number12
Publication statusPublished - 2012 Jun 15


Dive into the research topics of 'Total synthesis of (-)-polycavernoside A: Suzuki-Miyaura coupling approach'. Together they form a unique fingerprint.

Cite this