TY - GEN
T1 - Towards in vivo diffusion tensor MRI on human heart using edge-preserving regularization
AU - Frindel, Carole
AU - Robini, Marc
AU - Rapacchi, Stanislas
AU - Stephant, Eric
AU - Zhu, Yue Min
AU - Croisille, Pierre
PY - 2007
Y1 - 2007
N2 - We investigate the noise sensitivity in various Diffusion Tensor MRI acquisition protocols in sixteen human ex vivo hearts. In particular, we compare the accuracy of protocols with various numbers of excitations and diffusion sensitizing directions for estimating the principal diffusion directions in the myocardium. It is observed that noise sensitivity decreases as the number of excitations and the number of sensitizing directions increase (and hence as the acquisition time increases). To reduce the effects of noise and to improve the results obtained with a smaller number of excitations and/or a smaller number of sensitizing directions, we introduce a 3-D edge-preserving regularization method operating on diffusion weighted images. It allows to maintain the quality of the principal diffusion direction field while minimizing the acquisition time, which is a necessary step for in vivo diffusion tensor MR imaging of the human heart.
AB - We investigate the noise sensitivity in various Diffusion Tensor MRI acquisition protocols in sixteen human ex vivo hearts. In particular, we compare the accuracy of protocols with various numbers of excitations and diffusion sensitizing directions for estimating the principal diffusion directions in the myocardium. It is observed that noise sensitivity decreases as the number of excitations and the number of sensitizing directions increase (and hence as the acquisition time increases). To reduce the effects of noise and to improve the results obtained with a smaller number of excitations and/or a smaller number of sensitizing directions, we introduce a 3-D edge-preserving regularization method operating on diffusion weighted images. It allows to maintain the quality of the principal diffusion direction field while minimizing the acquisition time, which is a necessary step for in vivo diffusion tensor MR imaging of the human heart.
UR - http://www.scopus.com/inward/record.url?scp=57649185428&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=57649185428&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2007.4353717
DO - 10.1109/IEMBS.2007.4353717
M3 - Conference contribution
AN - SCOPUS:57649185428
SN - 1424407885
SN - 9781424407880
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 6007
EP - 6010
BT - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
T2 - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Y2 - 23 August 2007 through 26 August 2007
ER -