Traditional chinese medicine for treatment of dementia

Koh Iwasaki, Shin Takayama

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Dementia has been considered as a disease since the seventeenth century in traditional Asian medicine. In the nineteenth century, Wan Qingren described about dementia in a scientific manner at first time in the world. Recently, a traditional herbal medicine yokukansan (YKS) is paid attention to ameliorate behavioral and psychological symptoms of dementia (BPSD) without deterioration of extrapyramidal symptoms. YKS improves BPSD and ADL of demented people. Also, it ameliorates hallucination of dementia with Lewy bodies (DLB). Pharmacological mechanism of YKS is mainly owing to Uncaria and contained alkaloids related to serotonergic and glutamatergic functions.

Original languageEnglish
Title of host publicationDementia with Lewy Bodies
Subtitle of host publicationClinical and Biological Aspects
PublisherSpringer Japan
Number of pages7
ISBN (Electronic)9784431559481
ISBN (Print)9784431559467
Publication statusPublished - 2016 Jan 1


  • BPSD
  • DLB
  • Traditional Asian medicine
  • Yokukansan


Dive into the research topics of 'Traditional chinese medicine for treatment of dementia'. Together they form a unique fingerprint.

Cite this