Transit characteristics of a deformed neutrophil through a moderate constriction

Atsushi Shirai, Ryo Fujita, Toshiyuki Hayase

Research output: Contribution to journalConference articlepeer-review


This paper deals with the transit of a neutrophil through narrow capillary segments. In the simulation, the segments are modeled by arc-shaped constrictions arranged in a straight pipeline. Initially the spherical cell deforms in transit through the first constriction. We focus on the transit time of the deformed cell through the second constriction. We investigate the effects of segment geometry on the transit time. Finally, it is shown that the transit time is independent of the shape of the first segment so long as it is organized by the entrance cell radius.

Original languageEnglish
Pages (from-to)133-134
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Publication statusPublished - 2003
Event2003 ASME International Mechanical Engineering Congress - Washington, DC., United States
Duration: 2003 Nov 152003 Nov 21


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