TY - JOUR
T1 - Utility of cyclodextrin in mobile phase for high-performance liquid chromatographic separation of bufadienolides
AU - Shimada, Kazutake
AU - Kurata, Youko
AU - Oe, Tomoyuki
N1 - Funding Information:
ACKNOWLEDGEMENTS We thank Dr. Y. Kamano (Arizona State Univ.) for providing cinobufotalin. This work was supported by grants from the Ministry of Education, Science and Culture, Japan, Project Research Found from Graduate School of Natural Science and Technology, Kanazawa University and Takeda Research Foundation, which are gratefully acknowledged.
PY - 1990
Y1 - 1990
N2 - The chromatographic behavior of bufadienolides including conjugates was examined by the addition of Y-cyclodextrin to the mobile phase in reversed-phase high-performance liquid chromatography. The capacity factor of sulfate or glucuronide was decreased sharply by the additive. The separation of bufadienolides, unseparable under the usual method, was much improved by the addition of y-cyclodextrin.
AB - The chromatographic behavior of bufadienolides including conjugates was examined by the addition of Y-cyclodextrin to the mobile phase in reversed-phase high-performance liquid chromatography. The capacity factor of sulfate or glucuronide was decreased sharply by the additive. The separation of bufadienolides, unseparable under the usual method, was much improved by the addition of y-cyclodextrin.
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U2 - 10.1080/01483919008051801
DO - 10.1080/01483919008051801
M3 - Article
AN - SCOPUS:0025360790
SN - 0148-3919
VL - 13
SP - 493
EP - 504
JO - Journal of Liquid Chromatography
JF - Journal of Liquid Chromatography
IS - 3
ER -