Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system

Rui Lima; Shigeo Wada; Shuji Tanaka; Motohiro Takeda; Ken Ichi Tsubota; Takuji Ishikawa; Takami Yamaguchi

doi:10.1007/978-3-540-36841-0_79

Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system

Rui Lima, Shigeo Wada, Shuji Tanaka, Motohiro Takeda, Ken Ichi Tsubota, Takuji Ishikawa, Takami Yamaguchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

4 Citations (Scopus)

Abstract

This paper examines the ability to measure the velocity of both physiological saline (PS) and in vitro blood in a rectangular polydimethysiloxane (PDMS) microchannel by means of the confocal micro-PIV system. The PDMS microchannel, was fabricated by conventional soft lithography, had a microchannel near to a perfect rectangular shape (300μm wide, 45μm deep) and was optically transparent, which is suitable to measure both PS and in vitro blood using the confocal system. By using this latter combination, the measurements of trace particles seeded in the flow were performed for both fluids at a constant flow rate (Re=0.021). Generally, all the velocity profiles were found to be markedly blunt in the central region mainly due to the low aspect ratio (h/w=0.15) of the rectangular microchannel. Predictions by a theoretical model for the rectangular microchannel have showed fairly good correspondence with the experimental micro-PIV results for the PS fluid. Conversely, for the in vitro blood with 20% haematocrit, small fluctuations were found on velocity profiles.

Original language	English
Title of host publication	IFMBE Proceedings
Editors	Sun I. Kim, Tae Suk Suh
Publisher	Springer Verlag
Pages	283-286
Number of pages	4
Edition	1
ISBN (Print)	9783540368397
DOIs	https://doi.org/10.1007/978-3-540-36841-0_79
Publication status	Published - 2007
Event	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: 2006 Aug 27 → 2006 Sept 1

Publication series

Name	IFMBE Proceedings
Number	1
Volume	14
ISSN (Print)	1680-0737
ISSN (Electronic)	1433-9277

Conference

Conference	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/Territory	Korea, Republic of
City	Seoul
Period	06/8/27 → 06/9/1

Keywords

Blood flow
Confocal micro-PIV
Microcirculation
PDMS microchannel
Red blood cells

Access to Document

10.1007/978-3-540-36841-0_79

Cite this

Lima, R., Wada, S., Tanaka, S., Takeda, M., Tsubota, K. I., Ishikawa, T., & Yamaguchi, T. (2007). Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system. In S. I. Kim, & T. S. Suh (Eds.), IFMBE Proceedings (1 ed., pp. 283-286). (IFMBE Proceedings; Vol. 14, No. 1). Springer Verlag. https://doi.org/10.1007/978-3-540-36841-0_79

@inproceedings{7ad7d29c86ef47e5bfd0bfd76d5b3e34,

title = "Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system",

abstract = "This paper examines the ability to measure the velocity of both physiological saline (PS) and in vitro blood in a rectangular polydimethysiloxane (PDMS) microchannel by means of the confocal micro-PIV system. The PDMS microchannel, was fabricated by conventional soft lithography, had a microchannel near to a perfect rectangular shape (300μm wide, 45μm deep) and was optically transparent, which is suitable to measure both PS and in vitro blood using the confocal system. By using this latter combination, the measurements of trace particles seeded in the flow were performed for both fluids at a constant flow rate (Re=0.021). Generally, all the velocity profiles were found to be markedly blunt in the central region mainly due to the low aspect ratio (h/w=0.15) of the rectangular microchannel. Predictions by a theoretical model for the rectangular microchannel have showed fairly good correspondence with the experimental micro-PIV results for the PS fluid. Conversely, for the in vitro blood with 20% haematocrit, small fluctuations were found on velocity profiles.",

keywords = "Blood flow, Confocal micro-PIV, Microcirculation, PDMS microchannel, Red blood cells",

author = "Rui Lima and Shigeo Wada and Shuji Tanaka and Motohiro Takeda and Tsubota, {Ken Ichi} and Takuji Ishikawa and Takami Yamaguchi",

note = "Publisher Copyright: {\textcopyright} International Federation for Medical and Biological Engineering 2007.; 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 ; Conference date: 27-08-2006 Through 01-09-2006",

year = "2007",

doi = "10.1007/978-3-540-36841-0_79",

language = "English",

isbn = "9783540368397",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

number = "1",

pages = "283--286",

editor = "Kim, {Sun I.} and Suh, {Tae Suk}",

booktitle = "IFMBE Proceedings",

address = "Germany",

edition = "1",

}

Lima, R, Wada, S, Tanaka, S, Takeda, M, Tsubota, KI, Ishikawa, T & Yamaguchi, T 2007, Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system. in SI Kim & TS Suh (eds), IFMBE Proceedings. 1 edn, IFMBE Proceedings, no. 1, vol. 14, Springer Verlag, pp. 283-286, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 06/8/27. https://doi.org/10.1007/978-3-540-36841-0_79

Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system. / Lima, Rui; Wada, Shigeo; Tanaka, Shuji et al.
IFMBE Proceedings. ed. / Sun I. Kim; Tae Suk Suh. 1. ed. Springer Verlag, 2007. p. 283-286 (IFMBE Proceedings; Vol. 14, No. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system

AU - Lima, Rui

AU - Wada, Shigeo

AU - Tanaka, Shuji

AU - Takeda, Motohiro

AU - Tsubota, Ken Ichi

AU - Ishikawa, Takuji

AU - Yamaguchi, Takami

N1 - Publisher Copyright: © International Federation for Medical and Biological Engineering 2007.

PY - 2007

Y1 - 2007

N2 - This paper examines the ability to measure the velocity of both physiological saline (PS) and in vitro blood in a rectangular polydimethysiloxane (PDMS) microchannel by means of the confocal micro-PIV system. The PDMS microchannel, was fabricated by conventional soft lithography, had a microchannel near to a perfect rectangular shape (300μm wide, 45μm deep) and was optically transparent, which is suitable to measure both PS and in vitro blood using the confocal system. By using this latter combination, the measurements of trace particles seeded in the flow were performed for both fluids at a constant flow rate (Re=0.021). Generally, all the velocity profiles were found to be markedly blunt in the central region mainly due to the low aspect ratio (h/w=0.15) of the rectangular microchannel. Predictions by a theoretical model for the rectangular microchannel have showed fairly good correspondence with the experimental micro-PIV results for the PS fluid. Conversely, for the in vitro blood with 20% haematocrit, small fluctuations were found on velocity profiles.

AB - This paper examines the ability to measure the velocity of both physiological saline (PS) and in vitro blood in a rectangular polydimethysiloxane (PDMS) microchannel by means of the confocal micro-PIV system. The PDMS microchannel, was fabricated by conventional soft lithography, had a microchannel near to a perfect rectangular shape (300μm wide, 45μm deep) and was optically transparent, which is suitable to measure both PS and in vitro blood using the confocal system. By using this latter combination, the measurements of trace particles seeded in the flow were performed for both fluids at a constant flow rate (Re=0.021). Generally, all the velocity profiles were found to be markedly blunt in the central region mainly due to the low aspect ratio (h/w=0.15) of the rectangular microchannel. Predictions by a theoretical model for the rectangular microchannel have showed fairly good correspondence with the experimental micro-PIV results for the PS fluid. Conversely, for the in vitro blood with 20% haematocrit, small fluctuations were found on velocity profiles.

KW - Blood flow

KW - Confocal micro-PIV

KW - Microcirculation

KW - PDMS microchannel

KW - Red blood cells

UR - http://www.scopus.com/inward/record.url?scp=84958238231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84958238231&partnerID=8YFLogxK

U2 - 10.1007/978-3-540-36841-0_79

DO - 10.1007/978-3-540-36841-0_79

M3 - Conference contribution

AN - SCOPUS:84958238231

SN - 9783540368397

T3 - IFMBE Proceedings

SP - 283

EP - 286

BT - IFMBE Proceedings

A2 - Kim, Sun I.

A2 - Suh, Tae Suk

PB - Springer Verlag

T2 - 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006

Y2 - 27 August 2006 through 1 September 2006

ER -

Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system

Abstract

Publication series

Conference

Keywords

Access to Document

Other files and links

Fingerprint

Cite this