A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.
|Number of pages||2|
|Journal||Chemical and Pharmaceutical Bulletin|
|Publication status||Published - 2001|
- Solid-phase synthesis
ASJC Scopus subject areas
- Drug Discovery