Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis: Polymer-supported glycosyl donor

S. Manabe; Y. Ito

doi:10.1248/cpb.49.1234

Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis: Polymer-supported glycosyl donor

S. Manabe, Y. Ito

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.

Original language	English
Pages (from-to)	1234-1235
Number of pages	2
Journal	Chemical and Pharmaceutical Bulletin
Volume	49
Issue number	9
DOIs	https://doi.org/10.1248/cpb.49.1234
Publication status	Published - 2001
Externally published	Yes

Keywords

Linker
Oligosaccharide
Solid-phase synthesis

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.49.1234

Cite this

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abstract = "A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.",

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T1 - Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis

T2 - Polymer-supported glycosyl donor

AU - Manabe, S.

AU - Ito, Y.

PY - 2001

Y1 - 2001

N2 - A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.

AB - A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.

KW - Linker

KW - Oligosaccharide

KW - Solid-phase synthesis

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DO - 10.1248/cpb.49.1234

M3 - Article

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AN - SCOPUS:0034843994

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EP - 1235

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 9

ER -

Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis: Polymer-supported glycosyl donor

Abstract

Keywords

ASJC Scopus subject areas

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