高度教養教育機構・学生支援開発部門

研究成果

年別の研究成果 1990 2011 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 445 Article
• 35 Review article
• 11 Comment/debate
• 10 Editorial
• 13 その他
  • 8 Letter
  • 3 Chapter
  • 1 Paper
  • 1 Short survey

年別の研究成果

年別の研究成果

検索結果

• 2023

  Postreperfusion Syndrome Presenting as Posttransplant Portal Hypertension due to Prolonged Elevation of Pulmonary Vascular Resistance and the Role of Nitroglycerin in Diagnosis and Treatment: A Case Report of Budd-Chiari Syndrome

  Kawaji, T., Toyama, H., Yoshida, N., Moteki, S., Sasaki, A., Sasaki, K., Fujio, A., Tokodai, K., Miyagi, S. & Yamauchi, M., 2023, In: Tohoku Journal of Experimental Medicine. 259, 2, p. 121-126 6 p.

  研究成果: Article › 査読

  Open Access

  • Syndrome 100%
  • Portal Hypertension 77%
  • Glyceryl Trinitrate 55%
  • Transplantation 44%
  • Lung Vascular Resistance 44%

• Reduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents

  Shiga, H., Takahashi, T., Shiraki, M., Kojima, Y., Tsuji, T., Takagi, S., Hiramoto, K., Yokoyama, N., Sugimura, M., Iwabuchi, M., Endo, K., Onodera, M., Sato, Y., Shimodaira, Y., Nomura, E., Kikuchi, T., Chiba, H., Oomori, S., Kudo, H., Kumada, K., & 10 othersNagaie, S., Ogishima, S., Nagami, F., Shimoyama, Y., Moroi, R., Kuroha, M., Kakuta, Y., Ishige, T., Kinouchi, Y. & Masamune, A., 2023, In: Scandinavian journal of gastroenterology. 58, 4, p. 360-367 8 p.

  研究成果: Article › 査読

  • Inflammatory Bowel Disease 100%
  • Patient 88%
  • Normal Human 66%
  • Chickenpox 66%
  • Seropositivity 55%

• Response to COVID-19 vaccine is reduced in patients with inflammatory bowel disease, but improved with additional dose

  Shiga, H., Kakuta, Y., An, K., Abe, Y., Fujimaki, S., Shimoyama, Y., Naito, T., Moroi, R., Kuroha, M., Khor, S. S., Kawai, Y., Tokunaga, K., Kinouchi, Y. & Masamune, A., 2023 1月, In: Journal of Gastroenterology and Hepatology (Australia). 38, 1, p. 44-51 8 p.

  研究成果: Article › 査読

  Open Access

  • COVID-19 100%
  • Dose 60%
  • Patient 50%
  • Vaccine 40%
  • Vaccine Efficacy 40%
  2 被引用数 (Scopus)
• 2022

  Adult Living Donor Liver Transplantation for the Carryover Patients After Kasai Operation Who Have a History of Multiple Laparotomies

  Miyagi, S., Sasaki, K., Tokodai, K., Fujio, A., Kashiwadate, T., Miyazawa, K., Matsumura, M., Kamei, T. & Unno, M., 2022 3月, In: Transplantation Proceedings. 54, 2, p. 430-434 5 p.

  研究成果: Article › 査読

  • Liver Transplantation 100%
  • Donor 100%
  • Adult 66%
  • Complication 41%
  • Stenosis 33%

• Analysis of the disease activity of ulcerative colitis with and without concomitant primary sclerosing cholangitis: An investigation using a nationwide database in Japan

  Yano, K., Moroi, R., Shiga, H., Tarasawa, K., Shimoyama, Y., Kuroha, M., Hamada, S., Kakuta, Y., Fushimi, K., Fujimori, K., Kinouchi, Y. & Masamune, A., 2022 1月, In: JGH Open. 6, 1, p. 50-56 7 p.

  研究成果: Article › 査読

  Open Access

  • Ulcerative Colitis 100%
  • Disease Activity 33%
  • Combination Therapy 22%
  • Surgery 22%
  • Odds Ratio 22%
  2 被引用数 (Scopus)

• A pilot study investigating the safety and feasibility of endoscopic dilation using a radial incision and cutting technique for benign strictures of the small intestine: a study protocol

  Moroi, R., Shiga, H., Nochioka, K., Shimoyama, Y., Kuroha, M., Kakuta, Y., Kinouchi, Y. & Masamune, A., 2022 12月, In: Pilot and Feasibility Studies. 8, 1, 85.

  研究成果: Article › 査読

  Open Access

  • Incision 100%
  • Small Intestine 83%
  • Surgery 50%
  • Stenosis 50%
  • Stricture 50%

• A retrospective investigation to establish new screening approach for the detection of patients at high risk of Fabry disease in male left ventricular hypertrophy patients

  Kubo, T., Amano, M., Takashio, S., Okumura, T., Yamamoto, S., Nabeta, T., Oikawa, M., Kurisu, S., Ochi, Y., Sugiura, K., Baba, Y., Kuroiwa, H., Hirota, T., Yamasaki, N., Ishii, S., Nochioka, K., Takeishi, Y., Yasuda, S., Tsujita, K., Izumi, C., & 1 othersKitaoka, H., 2022 10月, In: Journal of cardiology. 80, 4, p. 325-331 7 p.

  研究成果: Article › 査読

  Open Access

  • Fabry Disease 100%
  • Heart Left Ventricle Hypertrophy 91%
  • Prevalence 25%
  • Hypertrophic Cardiomyopathy 8%
  • Galactosidase 8%
  1 被引用数 (Scopus)

• Capsule Endoscopy Is Useful for Postoperative Tight Control Management in Patients with Crohn’s Disease

  Shiga, H., Abe, I., Kusaka, J., Shimoyama, Y., Moroi, R., Kuroha, M., Kakuta, Y., Kinouchi, Y. & Masamune, A., 2022 1月, In: Digestive Diseases and Sciences. 67, 1, p. 263-272 10 p.

  研究成果: Article › 査読

  • Capsule Endoscopy 100%
  • Symptom 21%
  • Therapeutic Procedure 21%
  • Lesion 15%
  • Follow up 10%
  2 被引用数 (Scopus)

• Cholesterol Granuloma of the Liver Mimicking Malignant Tumor: A Case Report

  Ishikawa, Y., Fujio, A., Tokodai, K., Kashiwadate, T., Miyazawa, K., Sasaki, K., Matsumura, M., Saitoh, Y., Tsuruoka, M., Inoue, J., Miyagi, S., Fujishima, F., Unno, M. & Kamei, T., 2022, In: Tohoku Journal of Experimental Medicine. 256, 3, p. 235-240 6 p.

  研究成果: Article › 査読

  Open Access

  • Liver 100%
  • Granuloma 87%
  • Lesion 62%
  • Patient 50%
  • Cholesterol 37%

• Crohn's Disease and Early Exposure to Thiopurines are Independent Risk Factors for Mosaic Chromosomal Alterations in Patients with Inflammatory Bowel Diseases

  MENDEL Study Group, 2022 4月 1, In: Journal of Crohn's and Colitis. 16, 4, p. 643-655 13 p.

  研究成果: Article › 査読

  • Chromosome Mosaicism 100%
  • Crohn's Disease 41%
  • Patient with Inflammatory Bowel Disease 33%
  • Mercaptopurine 25%
  • Patient with Crohn's Disease 25%
  3 被引用数 (Scopus)

• Electrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial

  Ogawa, S., Ohsaki, Y., Shimizu, M., Nako, K., Okamura, M., Kabayama, S., Tabata, K., Tanaka, Y. & Ito, S., 2022 1月, In: Diabetology International. 13, 1, p. 209-219 11 p.

  研究成果: Article › 査読

  • Water 100%
  • Hydrogen 83%
  • Homeostatic Model Assessment 41%
  • Homeostasis Model Assessment 41%
  • Maturity Onset Diabetes of the Young 33%
  5 被引用数 (Scopus)

• Endoscopic radial incision and cutting for benign stenosis of the lower gastrointestinal tract: An investigation of novel endoscopic treatment in multicenter trial

  Moroi, R., Shiga, H., Nochioka, K., Chiba, H., Shimoyama, Y., Kuroha, M., Tosa, M., Kakuta, Y., Kayaba, S., Takahashi, S., Kinouchi, Y. & Masamune, A., 2022 8月, In: Journal of Gastroenterology and Hepatology (Australia). 37, 8, p. 1554-1560 7 p.

  研究成果: Article › 査読

  • Incision 100%
  • Stenosis 28%
  • Symptom 21%
  • Patient 21%
  • Adverse Event 14%
  2 被引用数 (Scopus)

• Evaluation of a Capillary Microsampling Device for Analyzing Plasma Lenvatinib Concentration in Patients With Hepatocellular Carcinoma

  Saito, A., Kikuchi, M., Matsumoto, Y., Sugawara, E., Takao, G., Inomata, H., Takahashi, A., Sato, Y., Kumondai, M., Sato, Y., Sato, T., Ninomiya, M., Inoue, J., Maekawa, M. & Mano, N., 2022 12月 1, In: Therapeutic drug monitoring. 44, 6, p. 771-776 6 p.

  研究成果: Article › 査読

  Open Access

  • Lenvatinib 100%
  • Liver Cell Carcinoma 33%
  • Electrospray Ionization 16%
  • Therapeutic Drug Monitoring 16%
  • Anticarcinogen 8%

• Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease

  Suzuki, K., Kakuta, Y., Naito, T., Takagawa, T., Hanai, H., Araki, H., Sasaki, Y., Sakuraba, H., Sasaki, M., Hisamatsu, T., Motoya, S., Matsumoto, T., Onodera, M., Ishiguro, Y., Nakase, H., Andoh, A., Hiraoka, S., Shinozaki, M., Fujii, T., Katsurada, T., & 61 othersKobayashi, T., Fujiya, M., Otsuka, T., Oshima, N., Suzuki, Y., Sato, Y., Hokari, R., Noguchi, M., Ohta, Y., Matsuura, M., Kawai, Y., Tokunaga, K., Nagasaki, M., Kudo, H., Minegishi, N., Okamoto, D., Shimoyama, Y., Moroi, R., Kuroha, M., Shiga, H., Li, D., McGovern, D. P. B., Kinouchi, Y., Masamune, A., Ikeya, K., Nishida, A., Nakagawa, S., Miura, M., Toyonaga, T., Onodera, K., Takahara, M., Yanai, S., Ishihara, S., Nagahori, M., Matsuoka, K., Arai, K., Mizuno, S., Naganuma, M., Nakamura, S., Ishikawa, T., Nakajima, H., Terasaki, H., Saito, R., Amemiya, I., Ohyama, H., Korekawa, K., Iwaki, H., Takahashi, S., Makuuchi, M., Inomata, Y., Shimoda, F., Takahashi, T., Yano, K., Abe, I., Handa, T., Masu, Y., Hishinuma, K., Kanazawa, Y., Kimura, T., Negoro, K. & Kato, M., 2022 1月 1, In: Inflammatory Bowel Diseases. 28, 1, p. 21-31 11 p.

  研究成果: Article › 査読

  • Mesalazine 100%
  • Allergy 45%
  • Diarrhea 36%
  • Genetic Background 27%
  • Fever 27%
  7 被引用数 (Scopus)

• High Incidence of Lymph-node Metastasis in a Pancreatic-cancer Patient-derived Orthotopic Xenograft (PDOX) NOG-Mouse Model

  Sugisawa, N., Miyake, K., Higuchi, T., Oshiro, H., Park, J. H. O., Kawaguchi, K., Bouvet, M., Unno, M. & Hoffman, R. M., 2022 2月, In: Anticancer research. 42, 2, p. 739-743 5 p.

  研究成果: Article › 査読

  Open Access

  • Patient 100%
  • Xenograft 83%
  • Red Fluorescent Protein 83%
  • Neoplasm 66%
  • Metastatic Carcinoma 66%
  1 被引用数 (Scopus)

• Influence of skeletal muscle volume loss during lenvatinib treatment on prognosis in unresectable hepatocellular carcinoma: a multicenter study in Tohoku, Japan

  Fujita, M., Abe, K., Kuroda, H., Oikawa, T., Ninomiya, M., Masamune, A., Okumoto, K., Katsumi, T., Sato, W., Iijima, K., Endo, T., Fukuda, S., Tanabe, N., Numao, H., Takikawa, Y., Ueno, Y. & Ohira, H., 2022 12月, In: Scientific reports. 12, 1, 6479.

  研究成果: Article › 査読

  Open Access

  • Liver Cell Carcinoma 100%
  • Lenvatinib 100%
  • Atrophy 80%
  • Prognosis 60%
  • Overall Survival 60%
  3 被引用数 (Scopus)

• Long-term effectiveness of ustekinumab comparable to antitumor necrosis factor agents in patients with Crohn's disease

  Shiga, H., Tarasawa, K., Moroi, R., Makuuchi, M., Takahashi, T., Shimoyama, Y., Kuroha, M., Kakuta, Y., Fushimi, K., Fujimori, K., Kinouchi, Y. & Masamune, A., 2022 11月, In: Journal of Gastroenterology and Hepatology (Australia). 37, 11, p. 2105-2112 8 p.

  研究成果: Article › 査読

  Open Access

  • Ustekinumab 100%
  • Patient 50%
  • TNF Inhibitor 40%
  • Tumor Necrosis Factor Inhibitor 40%
  • Tumor Necrosis Factor 30%

• Non-Achievement of Alanine Aminotransferase Normalization Associated with the Risk of Hepatocellular Carcinoma during Nucleos(t)ide Analogue Therapies: A Multicenter Retrospective Study

  THERME Study Group, 2022 5月 1, In: Journal of Clinical Medicine. 11, 9, 2354.

  研究成果: Article › 査読

  Open Access

  • Hepatocellular Carcinoma 100%
  • Liver Cell Carcinoma 100%
  • Alanine Aminotransferase 50%
  • Alanine 50%
  • Patient 41%
  2 被引用数 (Scopus)

• Novel technique for recanalization of severe hepaticojejunal obstruction using a transseptal needle in a pediatric liver transplant recipient

  Sasaki, K., Ota, H., Miyagi, S., Tokodai, K., Fujio, A., Kashiwadate, T., Miyazawa, K., Matsumura, M., Saitoh, Y., Kanai, N., Nishimaki, H., Takase, K., Unno, M. & Kamei, T., 2022 3月, In: Pediatric Transplantation. 26, 2, e14160.

  研究成果: Article › 査読

  • Obstruction 100%
  • Stricture 60%
  • Catheter 60%
  • Puncture 40%
  • Surgical Anastomosis 40%

• Optimal Conditions for Oxygenated Subnormothermic Machine Perfusion for Liver Grafts Using a Novel Perfusion Device

  Nishimaki, H., Miyagi, S., Kashiwadate, T., Tokodai, K., Fujio, A., Miyazawa, K., Sasaki, K., Kamei, T. & Unno, M., 2022 3月, In: Transplantation Proceedings. 54, 2, p. 217-224 8 p.

  研究成果: Article › 査読

  • Perfusion 100%
  • Heart Death 57%
  • Donor 57%
  • Cytokine 42%
  • Liver Enzyme 42%

• Oxygenated Hypothermic Machine Perfusion of Kidney Transplantation from Donors After Cardiac Death Due to Long-Term Low Blood Pressure and Hypoxia: The First Case Report of a Clinical Trial Using a New Japanese Perfusion System

  Miyagi, S., Kashiwadate, T., Nishimaki, H., Tokodai, K., Fujio, A., Miyazawa, K., Sasaki, K., Matsumura, M., Unno, M., Kamei, T. & Matsuno, N., 2022 3月, In: Transplantation Proceedings. 54, 2, p. 225-229 5 p.

  研究成果: Article › 査読

  • Donor 100%
  • Heart Death 83%
  • Machine Perfusion 83%
  • Kidney Graft 50%
  • Perfusion 50%

• Serum leucine-rich alpha-2 glycoprotein as a predictive factor of endoscopic remission in Crohn's disease

  Abe, I., Shiga, H., Chiba, H., Miyazawa, T., Oomori, S., Shimoyama, Y., Moroi, R., Kuroha, M., Kakuta, Y., Kinouchi, Y. & Masamune, A., 2022 9月, In: Journal of Gastroenterology and Hepatology (Australia). 37, 9, p. 1741-1748 8 p.

  研究成果: Article › 査読

  • Spontaneous Remission 100%
  • Remission 100%
  • Leucine 50%
  • Alpha2 Glycoprotein 50%
  • Faecal Calprotectin 43%

• Systemic-pulmonary collateral supply associated with clinical severity of chronic thromboembolic pulmonary hypertension: a study using intra-aortic computed tomography angiography

  Sun, W., Ota, H., Sato, H., Yamamoto, S., Tatebe, S., Aoki, T., Sugimura, K., Tominaga, J., Shimokawa, H., Ueda, T. & Takase, K., 2022 11月, In: European Radiology. 32, 11, p. 7668-7679 12 p.

  研究成果: Article › 査読

  Open Access

  • Chronic Thromboembolic Pulmonary Hypertension 100%
  • Vein 100%
  • Computed Tomography Angiography 71%
  • Lung 71%
  • Perfusion 71%

• Usefulness of Thiel-Embalmed Cadavers for Training in Organ Procurement

  Mitsugashira, H., Tokodai, K., Nakanishi, W., Fujio, A., Kashiwadate, T., Miyazawa, K., Sasaki, K., Miyagi, S., Owada, Y., Unno, M. & Kamei, T., 2022 3月, In: Transplantation Proceedings. 54, 2, p. 230-232 3 p.

  研究成果: Article › 査読

  • Donor 100%
  • Athletic Training 83%
  • Training 83%
  • Organ Transplantation 50%
  • Cadaver 50%
  2 被引用数 (Scopus)

• Validity of Diagnostic Algorithms for Inflammatory Bowel Disease in Japanese Hospital Claims Data

  Takahashi, S., Obara, T., Kakuta, Y., Shimoyama, Y., Naito, T., Moroi, R., Kuroha, M., Shiga, H., Kinouchi, Y. & Masamune, A., 2022 7月 1, In: International journal of environmental research and public health. 19, 13, 7933.

  研究成果: Article › 査読

  Open Access

  • Inflammatory Bowel Disease 100%
  • ICD-10 62%
  • Patient 50%
  • Prescription Drug 37%
  • Diagnosis 25%
  1 被引用数 (Scopus)

• What is the impact of zinc deficiency for pancreatectomies in patients with pancreatic ductal adenocarcinoma?

  Iseki, M., Mizuma, M., Aoki, S., Kawaguchi, K., Masuda, K., Ishida, M., Ohtsuka, H., Nakagawa, K., Morikawa, T., Kamei, T. & Unno, M., 2022 3月, In: Pancreatology. 22, 2, p. 270-276 7 p.

  研究成果: Article › 査読

  • Zinc Deficiency 100%
  • Pancreas Adenocarcinoma 55%
  • Infectious Complication 55%
  • Pancreatectomy 55%
  • Patient 55%
  1 被引用数 (Scopus)
• 2021

  Analysis of the Long-Term Prognosis in Japanese Patients with Ulcerative Colitis Treated with New Therapeutic Agents and the Correlation between Prognosis and Disease Susceptibility Loci

  Hishinuma, K., Moroi, R., Okamoto, D., Shimoyama, Y., Kuroha, M., Shiga, H., Kakuta, Y., Kinouchi, Y. & Masamune, A., 2021 9月 1, In: Inflammatory Intestinal Diseases. 6, 3, p. 154-164 11 p.

  研究成果: Article › 査読

  Open Access

  • Therapeutic Agent 100%
  • Prognosis 75%
  • Surgery 37%
  • Ulcerative Colitis 37%
  • Prednisolone 37%

• Comprehensive Analysis of microRNA Profiles in Organoids Derived from Human Colorectal Adenoma and Cancer

  Nagai, H., Kuroha, M., Handa, T., Karasawa, H., Ohnuma, S., Naito, T., Moroi, R., Kanazawa, Y., Shiga, H., Hamada, S., Kakuta, Y., Naitoh, T., Kinouchi, Y., Shimosegawa, T. & Masamune, A., 2021 11月 1, In: Digestion. 102, 6, p. 860-869 10 p.

  研究成果: Article › 査読

  Open Access

  • Organoid 100%
  • microRNA 90%
  • Colorectal Adenoma 90%
  • MicroRNA 90%
  • Colorectal Cancer 63%
  2 被引用数 (Scopus)

• Doppler ultrasonography is a useful tool for the diagnosis of hemodynamics in congestive graft injury due to heart failure after liver transplantation: A case report

  Sasaki, K., Tokodai, K., Fujio, A., Miyagi, S., Unno, M. & Kamei, T., 2021 11月, In: International Journal of Surgery Case Reports. 88, 106569.

  研究成果: Article › 査読

  Open Access

  • Heart Failure 100%
  • Patient 100%
  • Injury 66%
  • Liver Transplantation 66%
  • Doppler Ultrasonography 66%

• Envelope proteins of hepatitis B virus: Molecular biology and involvement in carcinogenesis

  Inoue, J., Sato, K., Ninomiya, M. & Masamune, A., 2021 6月, In: Viruses. 13, 6, 1124.

  研究成果: Article › 査読

  Open Access

  • Hepatitis B Virus 100%
  • Hepatocyte 80%
  • Virus Envelope 60%
  • Protein 60%
  • Viral Envelope 60%
  3 被引用数 (Scopus)

• Factors Associated with Fibrosis during Colorectal Endoscopic Submucosal Dissection: Does Pretreatment Biopsy Potentially Elicit Submucosal Fibrosis and Affect Endoscopic Submucosal Dissection Outcomes?

  Kuroha, M., Shiga, H., Kanazawa, Y., Nagai, H., Handa, T., Ichikawa, R., Onodera, M., Naito, T., Moroi, R., Kimura, T., Endo, K., Kakuta, Y., Kinouchi, Y., Shimosegawa, T. & Masamune, A., 2021 6月 1, In: Digestion. 102, 4, p. 590-598 9 p.

  研究成果: Article › 査読

  Open Access

  • Fibrosis 100%
  • Endoscopic Submucosal Dissection 66%
  • Biopsy 50%
  • Surgery 33%
  • Neoplasm 16%
  9 被引用数 (Scopus)

• Hepatitis B Virus Reactivation with Discontinuation of Nucleoside Analogue in Patients Who Received Allogeneic Hematopoietic Stem Cell Transplantation

  Tsuruoka, M., Inoue, J., Onishi, Y., Ninomiya, M., Kakazu, E., Iwata, T., Sano, A., Sato, K., Harigae, H. & Masamune, A., 2021 1月, In: Case Reports in Gastroenterology. 15, 1, p. 178-187 10 p.

  研究成果: Article › 査読

  Open Access

  • Hepatitis B Virus 100%
  • Patient 87%
  • Hepatitis 62%
  • Hematopoietic Stem Cell Transplantation 50%
  • Hepatitis B Antigen 50%

• Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A)

  Kurosawa, R., Satoh, K., Nakata, T., Shindo, T., Kikuchi, N., Satoh, T., Siddique, M. A. H., Omura, J., Sunamura, S., Nogi, M., Takeuchi, Y., Miyata, S. & Shimokawa, H., 2021 3月 1, In: Arteriosclerosis, thrombosis, and vascular biology. 41, 3, p. 1205-1217 13 p.

  研究成果: Article › 査読

  Open Access

  • CD147 Antigen 100%
  • Cyclophilin A 75%
  • Celastrol 41%
  • Pulmonary Hypertension 33%
  • Heart Right Ventricle Failure 33%
  8 被引用数 (Scopus)

• Immunoglobulin subtype-coated bacteria are correlated with the disease activity of inflammatory bowel disease

  Masu, Y., Kanazawa, Y., Kakuta, Y., Shimoyama, Y., Onodera, M., Naito, T., Moroi, R., Kuroha, M., Kimura, T., Shiga, H., Kinouchi, Y. & Masamune, A., 2021 12月, In: Scientific reports. 11, 1, 16672.

  研究成果: Article › 査読

  Open Access

  • Bacterium 100%
  • Inflammatory Bowel Disease 75%
  • Immunoglobulin 62%
  • Disease Activity 62%
  • Intravenous Immunoglobulin 62%
  6 被引用数 (Scopus)

• Increased neutrophil–lymphocyte ratio predicts recurrence in patients with well-differentiated pancreatic neuroendocrine neoplasm based on the 2017 World Health Organization classification

  Miura, T., Ohtsuka, H., Aoki, T., Aoki, S., Hata, T., Takadate, T., Maeda, S., Ariake, K., Kawaguchi, K., Masuda, K., Ishida, M., Mizuma, M., Nakagawa, K., Morikawa, T., Fujishima, F., Kamei, T., Sasano, H. & Unno, M., 2021 12月, In: BMC Surgery. 21, 1, 176.

  研究成果: Article › 査読

  Open Access

  • Neoplasm 100%
  • Recurrent Disease 66%
  • Marker 50%
  • Inpatient 50%
  • Surgery 33%
  5 被引用数 (Scopus)

• Intracholecystic papillary neoplasm arising in the cystic duct and extending into common bile duct: a case report

  Iseki, M., Mizuma, M., Aoki, Y., Aoki, S., Hata, T., Takadate, T., Kawaguchi, K., Masuda, K., Ishida, M., Ohtsuka, H., Nakagawa, K., Hayashi, H., Morikawa, T., Kamei, T., Kume, K., Kanno, A., Masamune, A., Omori, Y., Ono, Y., Mizukami, Y., & 2 othersFurukawa, T. & Unno, M., 2021 4月, In: Clinical Journal of Gastroenterology. 14, 2, p. 668-677 10 p.

  研究成果: Article › 査読

  • Common Bile Duct 100%
  • Cystic Duct 85%
  • Neoplasm 71%
  • Bile Duct Cancer 42%
  • Endoscopic Retrograde Cholangiopancreatography 28%
  3 被引用数 (Scopus)

• Liquid Biopsy for Colorectal Adenoma: Is the Exosomal miRNA Derived from Organoid a Potential Diagnostic Biomarker?

  Handa, T., Kuroha, M., Nagai, H., Shimoyama, Y., Naito, T., Moroi, R., Kanazawa, Y., Shiga, H., Kakuta, Y., Kinouchi, Y. & Masamune, A., 2021 5月 12, In: Clinical and Translational Gastroenterology. 12, 5, p. E00356

  研究成果: Article › 査読

  Open Access

  • MicroRNA 100%
  • Electric Potential 30%
  • Liquid 30%
  • Colon 20%
  • Microarray 10%
  11 被引用数 (Scopus)

• Liver resections in patients with prior bilioenteric anastomosis are predisposed to develop organ/space surgical site infections and biliary leakage: results from a propensity score matching analysis

  Morikawa, T., Ishida, M., Iseki, M., Aoki, S., Hata, T., Kawaguchi, K., Ohtsuka, H., Mizuma, M., Hayashi, H., Nakagawa, K., Kamei, T. & Unno, M., 2021 4月, In: Surgery today. 51, 4, p. 526-536 11 p.

  研究成果: Article › 査読

  • Surgical Anastomosis 100%
  • Hepatectomy 60%
  • Surgical Infection 60%
  • Organ 50%
  • Bile Leakage 40%

• Plasma free amino acids are associated with sarcopenia in the course of hepatocellular carcinoma recurrence

  Sano, A., Tsuge, S., Kakazu, E., Iwata, T., Ninomiya, M., Tsuruoka, M., Inoue, J. & Masamune, A., 2021 4月, In: Nutrition. 84, 111007.

  研究成果: Article › 査読

  • Patient 100%
  • Sarcopenia 100%
  • Skeletal Muscle 85%
  • Amino Acid 85%
  • Plasma 85%
  4 被引用数 (Scopus)

• Reactivation of hepatitis C virus with severe hepatitis flare during steroid administration for interstitial pneumonia

  Sato, K., Inoue, J., Kakazu, E., Ninomiya, M., Iwata, T., Sano, A., Tsuruoka, M. & Masamune, A., 2021 8月, In: Clinical Journal of Gastroenterology. 14, 4, p. 1221-1226 6 p.

  研究成果: Article › 査読

  • Hepatitis C Virus 100%
  • Virus Reactivation 83%
  • Combination Therapy 50%
  • RNA 50%
  • Steroid 50%

• Reconstruction of Portal Vein and Superior Mesenteric Vein Using Superficial Femoral Vein Graft in Surgical Resection of Pancreatic Head Cancer-A Case Report

  Umino, Y., Mizuma, M., Akamatsu, D., Aoki, S., Iseki, M., Kawaguchi, K., Masuda, K., Ishida, M., Ohtsuka, H., Nakagawa, K., Morikawa, T., Kamei, T., Kume, K., Masamune, A. & Unno, M., 2021 12月 1, In: Gan to kagaku ryoho. Cancer & chemotherapy. 48, 13, p. 1783-1785 3 p.

  研究成果: Article › 査読

  • Hepatic Portal Vein 100%
  • Superior Mesenteric Vein 100%
  • Patient 66%
  • Surgery 50%
  • Femoral Vein 50%
  1 被引用数 (Scopus)

• Staging laparoscopy is mandatory for the treatment of pancreatic cancer to avoid missing radiologically negative metastases

  Takadate, T., Morikawa, T., Ishida, M., Aoki, S., Hata, T., Iseki, M., Miura, T., Ariake, K., Maeda, S., Kawaguchi, K., Masuda, K., Ohtsuka, H., Mizuma, M., Hayashi, H., Nakagawa, K., Motoi, F., Kamei, T., Naito, T. & Unno, M., 2021 5月, In: Surgery today. 51, 5, p. 686-694 9 p.

  研究成果: Article › 査読

  • Laparoscopy 100%
  • Pancreas Cancer 75%
  • Metastatic Carcinoma 50%
  • Patient 50%
  • Odds Ratio 37%
  14 被引用数 (Scopus)

• Steatotic Hepatocytes Release Mature VLDL Through Methionine and Tyrosine Metabolism in a Keap1-Nrf2–Dependent Manner

  Sano, A., Kakazu, E., Hamada, S., Inoue, J., Ninomiya, M., Iwata, T., Tsuruoka, M., Sato, K. & Masamune, A., 2021 9月, In: Hepatology. 74, 3, p. 1271-1286 16 p.

  研究成果: Article › 査読

  • Amino Acid 100%
  • Tyrosine 100%
  • Amino Acids 100%
  • Hepatocyte 83%
  • Fatty Liver 66%
  9 被引用数 (Scopus)

• The clinical practice of ulcerative colitis in elderly patients: An investigation using a nationwide database in Japan

  Moroi, R., Shiga, H., Tarasawa, K., Yano, K., Shimoyama, Y., Kuroha, M., Kakuta, Y., Fushimi, K., Fujimori, K., Kinouchi, Y. & Masamune, A., 2021 8月, In: JGH Open. 5, 8, p. 842-848 7 p.

  研究成果: Article › 査読

  Open Access

  • Elderly Patient 100%
  • Patient with Ulcerative Colitis 50%
  • Surgery 25%
  • Hospital 25%
  • Death 20%
  7 被引用数 (Scopus)

• The Exosome-Associated Tetraspanin CD63 Contributes to the Efficient Assembly and Infectivity of the Hepatitis B Virus

  Ninomiya, M., Inoue, J., Krueger, E. W., Chen, J., Cao, H., Masamune, A. & McNiven, M. A., 2021 7月, In: Hepatology Communications. 5, 7, p. 1238-1251 14 p.

  研究成果: Article › 査読

  Open Access

  • Hepatitis B Virus 100%
  • CD63 80%
  • Cells 40%
  • HBsAg 30%
  • Virus Particle 30%
  13 被引用数 (Scopus)

• Triple-Methyl Blockade with Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model

  Sugisawa, N., Yamamoto, J., Han, Q., Tan, Y., Tashiro, Y., Nishino, H., Inubushi, S., Hamada, K., Kawaguchi, K., Unno, M., Bouvet, M. & Hoffman, R. M., 2021, In: Pancreas. 50, 1, p. 93-98 6 p.

  研究成果: Article › 査読

  • Recombinant Methionine Gamma Lyase 100%
  • Azacitidine 62%
  • Cycloleucine 62%
  • Combination Therapy 50%
  • Pancreas Cancer 50%
  9 被引用数 (Scopus)
• 2020

  A case of localized tracheobronchial relapsing polychondritis with positive matrilin-1 staining

  Makiguchi, T., Koarai, A., Inoue, C., Aoyama, Y., Hirano, T., Ohe, T., Ichikawa, T., Shishikura, Y., Komuro, H., Tsukita, Y., Tode, N., Numakura, T., Saito, T., Sato, T., Mitsuhashi, Y., Tamada, T., Sugiura, H. & Ichinose, M., 2020 1月 29, In: BMC Rheumatology. 4, 1, 1.

  研究成果: Article › 査読

  Open Access

  • Relapsing Polychondritis 100%
  • Matrilin 100%
  • Patient 50%
  • Pathogenesis 30%
  • Auricular Cartilage 30%

• An Integrated Genomic and Transcriptomic Analysis Reveals Candidates of Susceptibility Genes for Crohn’s Disease in Japanese Populations

  Kakuta, Y., Ichikawa, R., Fuyuno, Y., Hirano, A., Umeno, J., Torisu, T., Watanabe, K., Asakura, A., Nakano, T., Izumiyama, Y., Okamoto, D., Naito, T., Moroi, R., Kuroha, M., Kanazawa, Y., Kimura, T., Shiga, H., Naito, T., Esaki, M., Kawai, Y., & 7 othersTokunaga, K., Nakamura, M., Matsumoto, T., Nagasaki, M., Kinouchi, Y., Unno, M. & Masamune, A., 2020 12月 1, In: Scientific reports. 10, 1, 10236.

  研究成果: Article › 査読

  Open Access

  • Expression Quantitative Trait Locus 100%
  • Expression Quantitative Trait Loci 100%
  • Crohn's Disease 85%
  • Genome Wide Association Study 57%
  • Genome-Wide Association Study 57%
  4 被引用数 (Scopus)

• A Novel Anionic-phosphate-platinum Complex Effectively Targets a Cisplatinum-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model

  Igarashi, K., Kawaguchi, K., Yamamoto, N., Hayashi, K., Kimura, H., Miwa, S., Higuchi, T., Taniguchi, Y., Yonezawa, H., Araki, Y., Morinaga, S., Misra, S., Nelson, S. D., Dry, S. M., Yunfeng, L. I., Odani, A., Singh, S. R. A. M., Tsuchiya, H. & Hoffman, R. M., 2020, In: Cancer Genomics and Proteomics. 17, 3, p. 217-223 7 p.

  研究成果: Article › 査読

  Open Access

  • Patient 100%
  • Xenograft 71%
  • Osteosarcoma 57%
  • Neoplasm 42%
  • Mouse Model 42%
  7 被引用数 (Scopus)

• A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations

  Zhang, Z., Hu, K., Miyake, K., Kiyuna, T., Oshiro, H., Wangsiricharoen, S., Kawaguchi, K., Higuchi, T., Razmjooei, S., Miyake, M., Chawla, S. P., Singh, S. R. & Hoffman, R. M., 2020 12月, In: Scientific reports. 10, 1, 20105.

  研究成果: Article › 査読

  Open Access

  • Drug Combination 100%
  • Patient 75%
  • Liver Metastasis 62%
  • Xenograft 50%
  • Nude Mouse 37%
  4 被引用数 (Scopus)