Hiroshi Kadokura

2021

Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca²⁺-ATPase SERCA2b

Zhang, Y., Watanabe, S., Tsutsumi, A., Kadokura, H., Kikkawa, M. & Inaba, K., 2021 10月 1, In: EMBO Journal. 40, 19, e108482.

研究成果: Article › 査読

3 被引用数 (Scopus)

2020

Characterization of the endoplasmic reticulum–resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding

Kanemura, S., Sofia, E. F., Hirai, N., Okumura, M., Kadokura, H. & Inaba, K., 2020 9月 4, In: Journal of Biological Chemistry. 295, 36, p. 12772-12785 14 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

Observing the nonvectorial yet cotranslational folding of a multidomain protein, LDL receptor, in the ER of mammalian cells

Kadokura, H., Dazai, Y., Fukuda, Y., Hirai, N., Nakamura, O. & Inaba, K., 2020 7月 14, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16401-16408 8 p.

研究成果: Article › 査読

Open Access

6 被引用数 (Scopus)

2018

Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member

Fujimoto, T., Nakamura, O., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K. & Kadokura, H., 2018 11月 30, In: Journal of Biological Chemistry. 293, 48, p. 18421-18433 13 p.

研究成果: Article › 査読

Open Access

11 被引用数 (Scopus)

IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells

Tsuchiya, Y., Saito, M., Kadokura, H., Miyazaki, J. I., Tashiro, F., Imagawa, Y., Iwawaki, T. & Kohno, K., 2018 4月 1, In: Journal of Cell Biology. 217, 4, p. 1287-1301 15 p.

研究成果: Article › 査読

Open Access

67 被引用数 (Scopus)

2015

Structures and functions of protein disulfide isomerase family members involved in proteostasis in the endoplasmic reticulum

Okumura, M., Kadokura, H. & Inaba, K., 2015 5月 19, In: Free Radical Biology and Medicine. 83, p. 314-322 9 p.

研究成果: Article › 査読

78 被引用数 (Scopus)

2014

Inhibition of the functional interplay between endoplasmic reticulum (ER) Oxidoreduclin-1α (Ero1α) and protein-disulfide isomerase (PDI) by the endocrine disruptor bisphenol A

Okumura, M., Kadokura, H., Hashimoto, S., Yutani, K., Kanemura, S., Hikima, T., Hidaka, Y., Ito, L., Shiba, K., Masui, S., Imai, D., Imaoka, S., Yamaguchi, H. & Inaba, K., 2014 9月 26, In: Journal of Biological Chemistry. 289, 39, p. 27004-27018 15 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

2013

Identification of the redox partners of ERdj5/JPDI, a PDI family member, from an animal tissue

Kadokura, H., Saito, M., Tsuru, A., Hosoda, A., Iwawaki, T., Inaba, K. & Kohno, K., 2013 10月 18, In: Biochemical and biophysical research communications. 440, 2, p. 245-250 6 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Negative feedback by IRE1β optimizes mucin production in goblet cells

Tsuru, A., Fujimoto, N., Takahashi, S., Saito, M., Nakamura, D., Iwano, M., Iwawaki, T., Kadokura, H., Ron, D. & Kohno, K., 2013 2月 19, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 8, p. 2864-2869 6 p.

研究成果: Article › 査読

Open Access

114 被引用数 (Scopus)

The tRNA thiolation pathway modulates the intracellular redox state in Escherichia coli

Nakayashiki, T., Saito, N., Takeuchi, R., Kadokura, H., Nakahigashi, K., Wanner, B. L. & Mori, H., 2013 5月, In: Journal of bacteriology. 195, 9, p. 2039-2049 11 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

2012

A novel mammalian ER-located J-protein, DNAJB14, can accelerate ERAD of misfolded membrane proteins.

Sopha, P., Kadokura, H., Yamamoto, Y. H., Takeuchi, M., Saito, M., Tsuru, A. & Kohno, K., 2012, In: Cell structure and function. 37, 2, p. 177-187 11 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export

Chng, S. S., Xue, M., Garner, R. A., Kadokura, H., Boyd, D., Beckwith, J. & Kahne, D., 2012 9月 28, In: Science. 337, 6102, p. 1665-1668 4 p.

研究成果: Article › 査読

76 被引用数 (Scopus)

Overexpression of the rhodanese PspE, a single cysteine-containing protein, restores disulphide bond formation to an Escherichia coli strain lacking DsbA

Chng, S. S., Dutton, R. J., Denoncin, K., Vertommen, D., Collet, J. F., Kadokura, H. & Beckwith, J., 2012 9月, In: Molecular Microbiology. 85, 5, p. 996-1006 11 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

2011

Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro

Shinya, S., Kadokura, H., Imagawa, Y., Inoue, M., Yanagitani, K. & Kohno, K., 2011 7月, In: Nucleic acids research. 39, 12, p. 5245-5254 10 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA

Yanagitani, K., Kimata, Y., Kadokura, H. & Kohno, K., 2011 2月 4, In: Science. 331, 6017, p. 586-589 4 p.

研究成果: Article › 査読

150 被引用数 (Scopus)

2010

A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR.

Yamamoto, Y. H., Kimura, T., Momohara, S., Takeuchi, M., Tani, T., Kimata, Y., Kadokura, H. & Kohno, K., 2010 12月 23, In: Cell structure and function. 35, 2, p. 107-116 10 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in Escherichia coli

Ohtsu, I., Wiriyathanawudhiwong, N., Morigasaki, S., Nakatani, T., Kadokura, H. & Takagi, H., 2010 6月 4, In: Journal of Biological Chemistry. 285, 23, p. 17479-17487 9 p.

研究成果: Article › 査読

87 被引用数 (Scopus)

2009

Detecting Folding Intermediates of a Protein as It Passes through the Bacterial Translocation Channel

Kadokura, H. & Beckwith, J., 2009 9月 18, In: Cell. 138, 6, p. 1164-1173 10 p.

研究成果: Article › 査読

88 被引用数 (Scopus)

Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm

Eser, M., Masip, L., Kadokura, H., Georgiou, G. & Beckwith, J., 2009 2月 3, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 5, p. 1572-1577 6 p.

研究成果: Article › 査読

47 被引用数 (Scopus)

2008

NMR Solution Structure of the Integral Membrane Enzyme DsbB: Functional Insights into DsbB-Catalyzed Disulfide Bond Formation

Zhou, Y., Cierpicki, T., Jimenez, R. H. F., Lukasik, S. M., Ellena, J. F., Cafiso, D. S., Kadokura, H., Beckwith, J. & Bushweller, J. H., 2008 9月 26, In: Molecular Cell. 31, 6, p. 896-908 13 p.

研究成果: Article › 査読

148 被引用数 (Scopus)

2006

Conserved role of the linker α-helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB

Segatori, L., Murphy, L., Arredondo, S., Kadokura, H., Gilbert, H., Beckwith, J. & Georgiou, G., 2006 2月 24, In: Journal of Biological Chemistry. 281, 8, p. 4911-4919 9 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

2005

Mutational alterations of the key cis proline residue that cause accumulation of enzymatic reaction intermediates of DsbA, a member of the thioredoxin superfamily

Kadokura, H., Nichols, L. & Beckwith, J., 2005 2月, In: Journal of bacteriology. 187, 4, p. 1519-1522 4 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases

Sevier, C. S., Kadokura, H., Tam, V. C., Beckwith, J., Fass, D. & Kaiser, C. A., 2005 6月, In: Protein Science. 14, 6, p. 1630-1642 13 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

2004

Snapshots of DsbA in Action: Detection of Proteins in the Process of Oxidative Folding

Kadokura, H., Tian, H., Zander, T., Bardwell, J. C. A. & Beckwith, J., 2004 1月 23, In: Science. 303, 5657, p. 534-537 4 p.

研究成果: Article › 査読

187 被引用数 (Scopus)

2002

Biochemical characterization of horA-independent hop resistance mechanism in Lactobacillus brevis

Suzuki, K., Sami, M., Kadokura, H., Nakajima, H. & Kitamoto, K., 2002 6月 25, In: International Journal of Food Microbiology. 76, 3, p. 223-230 8 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA

Kadokura, H. & Beckwith, J., 2002 5月 15, In: EMBO Journal. 21, 10, p. 2354-2363 10 p.

研究成果: Article › 査読

81 被引用数 (Scopus)

2001

Cloning and sequencing of a gene encoding a novel salt stress-induced membrane protein from Rhodobacter sphaeroides f. sp. denitrificans

Xu, X. Y., Kadokura, H., Okubo, A., Kitamoto, K. & Yamazaki, S., 2001, In: Applied Microbiology and Biotechnology. 56, 3-4, p. 442-447 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Efficient export of alkaline phosphatase overexpressed from a multicopy plasmid requires degP, a gene encoding a periplasmic protease of Escherichia coli

Kadokura, H., Kawasaki, H., Yoda, K., Yamasaki, M. & Kitamoto, K., 2001, In: Journal of General and Applied Microbiology. 47, 3, p. 133-141 9 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

The expanding world of oxidative protein folding

Kadokura, H. & Beckwith, J., 2001 11月, In: Nature cell biology. 3, 11, p. E247-E249

研究成果: Article › 査読

17 被引用数 (Scopus)

2000

Production and product quality assessment of human hepatitis B virus pre-S2 antigen in submerged and solid-state cultures of Aspergillus oryzae

Maruyama, J. I., Ohnuma, H., Yoshikawa, A., Kadokura, H., Nakajima, H. & Kitamoto, K., 2000 1月 1, In: Journal of Bioscience and Bioengineering. 90, 1, p. 118-120 3 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Roles of a conserved arginine residue of DsbB in linking protein disulfide-bond-formation pathway to the respiratory chain of Escherichia coli

Kadokura, H., Bader, M., Tian, H., Bardwell, J. C. A. & Beckwith, J., 2000 9月 26, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 20, p. 10884-10889 6 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

1999

Immunological and molecular comparison of polyphenol oxidase in Rosaceae fruit trees

Haruta, M., Murata, M., Kadokura, H. & Homma, S., 1999 3月 20, In: Phytochemistry. 50, 6, p. 1021-1025 5 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

1998

A plasmid pRH45 of Lactobacillus brevis confers hop resistance

Sami, M., Suzuki, K., Sakamoto, K., Kadokura, H., Kitamoto, K. & Yoda, K., 1998, In: Journal of General and Applied Microbiology. 44, 5, p. 361-363 3 p.

研究成果: Article › 査読

43 被引用数 (Scopus)

Cloning genomic dna encoding apple polyphenol oxidase and comparison of the gene product in escherichia coli and in apple

Haruta, M., Murata, M., Hiraide, A., Kadokura, H., Yamasaki, M., Sakuta, M. & Shimizu, S., 1998, In: Bioscience, Biotechnology and Biochemistry. 62, 2, p. 358-362 5 p.

研究成果: Article › 査読

Open Access

34 被引用数 (Scopus)

Identification of a sulfhydryl-reducing agent-inducible protein highly homologous to protein synthesis elongation factor Tu in Bacillus subtilis

Wang, T., Kadokura, H., Yada, K. & Yamasaki, M., 1998 2月, In: Wei sheng wu xue bao = Acta microbiologica Sinica. 38, 1, p. 6-12 7 p.

研究成果: Article › 査読

1997

A new and rapid method for determination of beer-spoilage ability of lactobacilli

Sami, M., Yamashita, H., Kadokura, H., Kitamoto, K., Yoda, K. & Yamasaki, M., 1997, In: Journal of the American Society of Brewing Chemists. 55, 4, p. 137-140 4 p.

研究成果: Article › 査読

70 被引用数 (Scopus)

Hop-resistant Lactobacillus brevis contains a novel plasmid harboring a multidrug resistance-like gene

Sami, M., Yamashita, H., Hirono, T., Kadokura, H., Kitamoto, K., Yoda, K. & Yamasaki, M., 1997, In: Journal of Fermentation and Bioengineering. 84, 1, p. 1-6 6 p.

研究成果: Article › 査読

82 被引用数 (Scopus)

Identification of a disulfide bonded protein from cytoplasm of Bacillus subtilis

Wang, T., Hiroshi, K. & Makari, Y., 1997, In: Chinese Science Bulletin. 42, 20, p. 1756-1760 5 p.

研究成果: Article › 査読

Internal amino acid sequence analysis of proteins after limited proteolytic cleavage

Wang, T., Kadokura, H., Yoda, K. & Yamasaki, M., 1997 12月 1, In: Progress in Biochemistry and Biophysics. 24, 1, p. 68-71 4 p.

研究成果: Article › 査読

1996

Secretion of active subtilisin YaB by a simultaneous expression of separate pre-pro and pre-mature polypeptides in Bacillus subtilis

Chang, Y. C., Kadokura, H., Yoda, K. & Yamasaki, M., 1996 2月 15, In: Biochemical and biophysical research communications. 219, 2, p. 463-468 6 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

1995

bfr1⁺, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily

Nagao, K., Taguchi, Y., Arioka, M., Kadokura, H., Takatsuki, A., Yoda, K. & Yamasaki, M., 1995, In: Journal of bacteriology. 177, 6, p. 1536-1543 8 p.

研究成果: Article › 査読

62 被引用数 (Scopus)

Physiological and biochemical analysis of the effects of alkaline phosphatase overproduction in Escherichia coli

Kadokura, H., Watanabe, K., Tsuneizumi, K., Yoda, K. & Yamasaki, M., 1995, In: Journal of bacteriology. 177, 12, p. 3596-3600 5 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

1994

Enhancement of protein secretion by optimizing protein synthesis: isolation and characterization of Escherichia coli mutants with increased secretion ability of alkaline phosphatase

Kadokura, H., Yoda, K., Watanabe, S., Kikuchi, Y., Tamura, G. & Yamasaki, M., 1994 4月 1, In: Applied Microbiology and Biotechnology. 41, 2, p. 163-169 7 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

1990

Molecular cloning of the protocatechuate 4,5-dioxygenase genes of Pseudomonas paucimobilis

Noda, Y., Nishikawa, S., Shiozuka, K. I., Kadokura, H., Nakajima, H., Yoda, K., Katayama, Y., Morohoshi, N., Haraguchi, T. & Yamasaki, M., 1990, In: Journal of bacteriology. 172, 5, p. 2704-2709 6 p.

研究成果: Article › 査読

115 被引用数 (Scopus)

Production and secretion in Escherichia coli of hepatitis b virus pre-S2 antigen as fusion proteins with β-lactamase

Kadokura, H., Yoda, K., Imai, M. & Yamasaki, M., 1990, In: Applied and environmental microbiology. 56, 9, p. 2742-2747 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

1987

Secretion of Bacillus subtilis α-amylase in the periplasmic space of Escherichia coli

Tachibana, K. I., Yoda, K., Watanabe, S., Kadokura, H., Katayama, Y., Yamane, K., Yamasaki, M. & Tamura, G., 1987 1月 1, In: Journal of General Microbiology. 133, 7, p. 1775-1782 8 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

1986

Expression of the pre-S(2) gene of hepatitis B virus in Escherichia coli

Tachibana, K., Imai, M., Okamoto, H., Yoda, K., Kadokura, H., Katayama, Y. & Yamasaki, M., 1986 10月 1, In: Biotechnology Letters. 8, 10, p. 677-682 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

門倉 広

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門倉広