Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing

Ramin Banan Sadeghian; Jiuhui Han; João Ribas; Amir Nasajpour; Margaux Duchamp; Seyed Ali Mousavi Shaegh; Serge Ostrovidov; Sahar Salehi; Mingwei Chen; Ali Khademhosseini

doi:10.1109/NANO.2016.7751411

Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing

Ramin Banan Sadeghian, Jiuhui Han, João Ribas, Amir Nasajpour, Margaux Duchamp, Seyed Ali Mousavi Shaegh, Serge Ostrovidov, Sahar Salehi, Mingwei Chen, Ali Khademhosseini

学際科学フロンティア研究所・新領域創成研究部

研究成果: Conference contribution

抄録

We employed the large surface-to-volume ratio of nanoporous gold (NPG) to build a set of highly sensitive superoxide electrochemical biosensors. Once functionalized with cytochrome-c (cyt-c) the NPG-based electrodes displayed a superoxide sensitivity of 0.24 nA nM-1 and a low-level of detection of 5 nM towards superoxide. The planar electrodes were then interfaced with HUVEC cells and were able to detect the release of extracellular superoxide upon stimulation with an endogenous superoxide producer. In addition, we studied the superoxide sensing performance of a three-dimensional (3D) macroporous mesh of gold decorated with NPG as a potential ultrasensitive superoxide biosensor.

本文言語	English
ホスト出版物のタイトル	16th International Conference on Nanotechnology - IEEE NANO 2016
出版社	Institute of Electrical and Electronics Engineers Inc.
ページ	19-21
ページ数	3
ISBN（電子版）	9781509039142
DOI	https://doi.org/10.1109/NANO.2016.7751411
出版ステータス	Published - 2016 11月 21
イベント	16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, Japan 継続期間: 2016 8月 22 → 2016 8月 25

出版物シリーズ

名前	16th International Conference on Nanotechnology - IEEE NANO 2016

Other

Other	16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
国/地域	Japan
City	Sendai
Period	16/8/22 → 16/8/25

ASJC Scopus subject areas

電子材料、光学材料、および磁性材料
原子分子物理学および光学

文献へのアクセス

10.1109/NANO.2016.7751411

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引用スタイル

Sadeghian, R. B., Han, J., Ribas, J., Nasajpour, A., Duchamp, M., Shaegh, S. A. M., Ostrovidov, S., Salehi, S., Chen, M., & Khademhosseini, A. (2016). Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing. In 16th International Conference on Nanotechnology - IEEE NANO 2016 (pp. 19-21). [7751411] (16th International Conference on Nanotechnology - IEEE NANO 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2016.7751411

Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing. / Sadeghian, Ramin Banan; Han, Jiuhui; Ribas, João その他.
16th International Conference on Nanotechnology - IEEE NANO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. 19-21 7751411 (16th International Conference on Nanotechnology - IEEE NANO 2016).

研究成果: Conference contribution

Sadeghian, RB, Han, J, Ribas, J, Nasajpour, A, Duchamp, M, Shaegh, SAM, Ostrovidov, S, Salehi, S, Chen, M & Khademhosseini, A 2016, Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing. in 16th International Conference on Nanotechnology - IEEE NANO 2016., 7751411, 16th International Conference on Nanotechnology - IEEE NANO 2016, Institute of Electrical and Electronics Engineers Inc., pp. 19-21, 16th IEEE International Conference on Nanotechnology - IEEE NANO 2016, Sendai, Japan, 16/8/22. https://doi.org/10.1109/NANO.2016.7751411

Sadeghian RB, Han J, Ribas J, Nasajpour A, Duchamp M, Shaegh SAM その他. Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing. In 16th International Conference on Nanotechnology - IEEE NANO 2016. Institute of Electrical and Electronics Engineers Inc. 2016. p. 19-21. 7751411. (16th International Conference on Nanotechnology - IEEE NANO 2016). doi: 10.1109/NANO.2016.7751411

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abstract = "We employed the large surface-to-volume ratio of nanoporous gold (NPG) to build a set of highly sensitive superoxide electrochemical biosensors. Once functionalized with cytochrome-c (cyt-c) the NPG-based electrodes displayed a superoxide sensitivity of 0.24 nA nM-1 and a low-level of detection of 5 nM towards superoxide. The planar electrodes were then interfaced with HUVEC cells and were able to detect the release of extracellular superoxide upon stimulation with an endogenous superoxide producer. In addition, we studied the superoxide sensing performance of a three-dimensional (3D) macroporous mesh of gold decorated with NPG as a potential ultrasensitive superoxide biosensor.",

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AU - Sadeghian, Ramin Banan

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AU - Ribas, João

AU - Nasajpour, Amir

AU - Duchamp, Margaux

AU - Shaegh, Seyed Ali Mousavi

AU - Ostrovidov, Serge

AU - Salehi, Sahar

AU - Chen, Mingwei

AU - Khademhosseini, Ali

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AB - We employed the large surface-to-volume ratio of nanoporous gold (NPG) to build a set of highly sensitive superoxide electrochemical biosensors. Once functionalized with cytochrome-c (cyt-c) the NPG-based electrodes displayed a superoxide sensitivity of 0.24 nA nM-1 and a low-level of detection of 5 nM towards superoxide. The planar electrodes were then interfaced with HUVEC cells and were able to detect the release of extracellular superoxide upon stimulation with an endogenous superoxide producer. In addition, we studied the superoxide sensing performance of a three-dimensional (3D) macroporous mesh of gold decorated with NPG as a potential ultrasensitive superoxide biosensor.

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Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing

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