TY - JOUR
T1 - Cardiac-related sympathetic nerve activity during circulation with only the left ventricular assist device
AU - Yambe, T.
AU - Nitta, S.
AU - Katahira, Y.
AU - Sonobe, T.
AU - Naganuma, S.
AU - Akiho, H.
AU - Chiba, S.
AU - Kakinuma, Y.
AU - Hayashi, H.
AU - Izutsu, K.
AU - Kikuchi, Y.
AU - Naganuma, T.
AU - Sugawara, S.
AU - Tanaka, M.
AU - Miura, M.
AU - Sato, N.
AU - Mohri, H.
AU - Yoshizawa, M.
AU - Takeda, H.
PY - 1992
Y1 - 1992
N2 - Circulatory maintenance with a left ventricular assist device (LVAD) alone during cardiac arrest until heart transplantation has been evaluated. To assess the effect on the autonomic nervous system, the sympathetic neurogram was analyzed by power spectrum and coherence function. LVAD were inserted between the left atrium and the descending aorta in seven adult mongrel dogs and ventricular fibrillation was induced electrically. Renal sympathetic nerve activity (RSNA) was detected by bipolar electrodes attached to the left renal sympathetic nerve. Values of squared coherence between the arterial pulse wave and RSNA were calculated. Under the condition of circulatory maintenance with only LVAD, coherence at the cardiac rhythm frequency was decreased, and coherence at the LVAD pumping rhythm frequency was increased. These results indicate that the arterial pulse wave observed during maintenance of the circulation with only LVAD contributed to the sympathetic neurogram.
AB - Circulatory maintenance with a left ventricular assist device (LVAD) alone during cardiac arrest until heart transplantation has been evaluated. To assess the effect on the autonomic nervous system, the sympathetic neurogram was analyzed by power spectrum and coherence function. LVAD were inserted between the left atrium and the descending aorta in seven adult mongrel dogs and ventricular fibrillation was induced electrically. Renal sympathetic nerve activity (RSNA) was detected by bipolar electrodes attached to the left renal sympathetic nerve. Values of squared coherence between the arterial pulse wave and RSNA were calculated. Under the condition of circulatory maintenance with only LVAD, coherence at the cardiac rhythm frequency was decreased, and coherence at the LVAD pumping rhythm frequency was increased. These results indicate that the arterial pulse wave observed during maintenance of the circulation with only LVAD contributed to the sympathetic neurogram.
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U2 - 10.1177/039139889201500109
DO - 10.1177/039139889201500109
M3 - Article
C2 - 1551728
AN - SCOPUS:0026572947
SN - 0391-3988
VL - 15
SP - 49
EP - 54
JO - International Journal of Artificial Organs
JF - International Journal of Artificial Organs
IS - 1
ER -