Concise synthesis of the C15-C38 fragment of okadaic acid: Application of the Suzuki-Miyaura reaction to spiroacetal synthesis

Haruhiko Fuwa; Keita Sakamoto; Takashi Muto; Makoto Sasaki

doi:10.1021/ol503491t

Concise synthesis of the C15-C38 fragment of okadaic acid: Application of the Suzuki-Miyaura reaction to spiroacetal synthesis

Haruhiko Fuwa, Keita Sakamoto, Takashi Muto, Makoto Sasaki

研究成果: Article › 査読

6 被引用数 (Scopus)

抄録

A concise synthetic entry to the C15-C38 fragment of okadaic acid by exploiting a Suzuki-Miyaura reaction for the rapid assembly of the spiroacetal substructures has been developed. The present synthesis was completed in 19 linear steps from a commercially available material, showcasing the efficiency of our synthetic strategy.

本文言語	English
ページ（範囲）	366-369
ページ数	4
ジャーナル	Organic letters
巻	17
号	2
DOI	https://doi.org/10.1021/ol503491t
出版ステータス	Published - 2015 1月 16

ASJC Scopus subject areas

生化学
物理化学および理論化学
有機化学

文献へのアクセス

10.1021/ol503491t

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引用スタイル

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abstract = "A concise synthetic entry to the C15-C38 fragment of okadaic acid by exploiting a Suzuki-Miyaura reaction for the rapid assembly of the spiroacetal substructures has been developed. The present synthesis was completed in 19 linear steps from a commercially available material, showcasing the efficiency of our synthetic strategy.",

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