@article{192edc31cbe84dd5a6e782502736057c,
title = "Convergent Synthesis of Taxol Skeleton via Decarbonylative Radical Coupling Reaction",
abstract = "The highly oxygenated 6/8/6-membered ABC-ring 2 of taxol was assembled in a convergent fashion. A decarbonylative radical reaction between α-alkoxyacyl telluride 4 and cyanocyclohexenone 5 linked the A- and C-rings and stereoselectively installed the C2- and C3-tertiary carbon centers of 3. After the C8-quaternary stereocenter was constructed, the C9-methyl ketone and the C11-vinyl triflate of 30 participated in Pd(0)-promoted cyclization of the eight-membered B-ring, giving rise to the taxol skeleton 2.",
author = "Hiroaki Matoba and Takahiro Watanabe and Masanori Nagatomo and Masayuki Inoue",
note = "Funding Information: This research was financially supported by Grants-in-Aid for Scientific Research (S) (17H06110) for Scientific Research on Innovative Areas (17H06452) to M.I. and Grants-in-Aid for Scientific Research (C) (16K08156) for Scientific Research on Innovative Areas (18H04384) to M.N. from JSPS. Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",
year = "2018",
month = dec,
day = "7",
doi = "10.1021/acs.orglett.8b03302",
language = "English",
volume = "20",
pages = "7554--7557",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "23",
}