Deoxycorticosterone-secreting adrenocortical carcinoma

Akihiro Yamamoto, Takushi Naroda, Susumu Kagawa, Yoshihumi Umaki, Yasumi Shintani, Toshiaki Sano, Hironobu Sasano

研究成果: Article査読

3 被引用数 (Scopus)

抄録

A case of DOC-secreting adrenocortical carcinoma in a 66-year-old man is reported. He had hypertension, hypokalemia, suppressed PRA, and excessive serum levels of DOC. His serum aldosterone level was normal. The resected adrenal mass weighed 230 g. Histologically, the tumor was mainly composed of compact cells associated with necrosis and atypical mitoses. Invasion of venous structure, sinusoids, and capsule was also present. Immunohistochemically, P450 C21 (21 -hydroxylase) was positive in many tumor cells, and P450 C17(17 α-hydroxylase) was intensely positive in a relatively small number of tumor cells. The patient died 9 months after operation due to rupture of metastatic liver tumor. Endocr Pathol 4:165-168, 1993.

本文言語English
ページ(範囲)165-168
ページ数4
ジャーナルEndocrine Pathology
4
3
DOI
出版ステータスPublished - 1993 9月

ASJC Scopus subject areas

  • 病理学および法医学
  • 内分泌学、糖尿病および代謝内科学
  • 内分泌学

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