@article{bde6db6451174fc0abf0ec2274c99fc6,
title = "Destabilization of DNA through interstrand crosslinking by UO22+",
abstract = "UO22+ was shown to form an interstrand crosslink between two different strands of a single DNA molecule. This crosslink hardly affected the hydrogen bonds between nucleobase pairs but destabilized the π-π stacking between the two nucleobases in the vicinity of UO22+-bound phosphate. Thereby, the fragility of the DNA backbone increased upon UO22+ binding.",
author = "Andr{\'e} Rossberg and Takaya Abe and Koji Okuwaki and Astrid Barkleit and Kaori Fukuzawa and Tatsuya Nakano and Yuji Mochizuki and Satoru Tsushima",
note = "Funding Information: This work was partially funded by the Ministry of Education, Culture, Sports, Science, and Technology of Japan (MEXT) under the framework {\textquoteleft}{\textquoteleft}Grant-in-Aid for Scientific Research B{\textquoteright}{\textquoteright} (16H04635). MEXT also supported this project as a Social and Scientific Priority Issue 6 (Accelerated Development of Innovative Clean Energy Systems) for the post-K supercomputing facility of Japan (FS2020). We thank A. C. Scheinost, J. Raff, K. Takao, Y. Komeiji, E. Miyoshi, and K. Fahmy for their assistance. Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",
year = "2019",
doi = "10.1039/c8cc09329f",
language = "English",
volume = "55",
pages = "2015--2018",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "14",
}