Early postirradiation changes in Na+ and fluid transport across alveolar epithelium in rats

S. Suzuki, M. Noda, Y. Abe, M. Sugita, S. Ono, T. Tanita, K. Koike, S. Fujimura

研究成果: ジャーナルへの寄稿学術論文査読

抄録

To study changes in Na+ and fluid transport that occur soon after irradiation of the thorax, we used fluid-filled isolated rat lungs. Irradiation 15 Gy of 60Co doubled the fluid absorption rate across the alveolar epithelium within 2 weeks, but fluid absorption had returned to the baseline values by 3 weeks after irradiation. The timing of this change in fluid absorption was parallel to the time course of Na+ escape across alveolar epithelium and the two correlated closely. These data suggest that a dysfunction of alveolar epithelial Na+ transport is involved in the development of pulmonary edema after irradiation of the thorax.

本文言語英語
ページ(範囲)167-172
ページ数6
ジャーナルRespiratory Investigation
35
2
出版ステータス出版済み - 1997

フィンガープリント

「Early postirradiation changes in Na+ and fluid transport across alveolar epithelium in rats」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル