TY - JOUR
T1 - Formation of bioactive N-doped TiO2 on Ti with visible light-induced antibacterial activity using NaOH, hot water, and subsequent ammonia atmospheric heat treatment
AU - Kawashita, Masakazu
AU - Endo, Naoko
AU - Watanabe, Tomoaki
AU - Miyazaki, Toshiki
AU - Furuya, Maiko
AU - Yokota, Kotoe
AU - Abiko, Yuki
AU - Kanetaka, Hiroyasu
AU - Takahashi, Nobuhiro
N1 - Funding Information:
This work was partially supported by a Grant-in-Aid for Scientific Research (B) (No. 25282139 ), from the Ministry of Education, Culture, Sports, Science, and Technology, Japan , and the Fujikura Foundation, Japan . The authors thank Ms. Ohmura and Prof. Goto of the Institute for Materials Research, Tohoku University, for the XPS measurements and data analysis.
Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Titanium (Ti) treated with NaOH and hot water, and heated in an ammmonia (NH3) gas atmosphere for 1 or 3 h exhibited in vitro apatite formation within 7 days when soaked in simulated body fluid (SBF). Moreover, the treated Ti decomposed methylene blue and showed excellent bactericidal activity against Escherichia coli under visible light irradiation. The surface treatment resulted in the formation of a fine network of N-doped anatase-type titania (TiO2-xNx) on the Ti surface, which was responsible for both the apatite formation in SBF and the visible light-induced antibacterial activity. These preliminary results highlight the efficacy of our simple method for producing novel bioactive Ti with visible light-induced antibacterial activity, which could be applied to orthopaedic and dental implants without the risk of infection.
AB - Titanium (Ti) treated with NaOH and hot water, and heated in an ammmonia (NH3) gas atmosphere for 1 or 3 h exhibited in vitro apatite formation within 7 days when soaked in simulated body fluid (SBF). Moreover, the treated Ti decomposed methylene blue and showed excellent bactericidal activity against Escherichia coli under visible light irradiation. The surface treatment resulted in the formation of a fine network of N-doped anatase-type titania (TiO2-xNx) on the Ti surface, which was responsible for both the apatite formation in SBF and the visible light-induced antibacterial activity. These preliminary results highlight the efficacy of our simple method for producing novel bioactive Ti with visible light-induced antibacterial activity, which could be applied to orthopaedic and dental implants without the risk of infection.
KW - Apatite
KW - Nitrogen
KW - Simulated body fluid
KW - Titania
KW - Titanium
KW - Visible light-induced antibacterial activity
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U2 - 10.1016/j.colsurfb.2016.05.017
DO - 10.1016/j.colsurfb.2016.05.017
M3 - Article
C2 - 27208442
AN - SCOPUS:84968724786
SN - 0927-7765
VL - 145
SP - 285
EP - 290
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
ER -