抄録
In this study, we demonstrate the use of surface plasmon interaction between Au nanoparticles (GPs) and a Au thin film for enhancement of surface plasmon resonance (SPR) spectroscopy sensing for DNA hybridization. In situ DNA hybridization with a Au-nanoparticle-attached probe DNA (DNA-GP) monolayer is monitored by SPR spectroscopy, and the results reveal that the DNA-GP allows detection of unlabeled target DNA with the large dynamic range of 1 pM to 10 μM.
本文言語 | English |
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ジャーナル | Japanese Journal of Applied Physics, Part 2: Letters |
巻 | 44 |
号 | 50-52 |
DOI | |
出版ステータス | Published - 2005 12月 16 |
ASJC Scopus subject areas
- 物理学および天文学(その他)