High-yielding synthesis of the anti-influenza neuramidase inhibitor (-)-oseltamivir by three "One-Pot" operations

Hayato Ishikawa, Takaki Suzuki, Yujiro Hayashi

研究成果: Article査読

348 被引用数 (Scopus)

抄録

Taking shortcuts: A remarkably short and high-yielding asymmetric total synthesis of (-)-oseltamivir takes advantage of organocatalysis and single-pot domino operations. The target, known as the drug Tamiflu, is prepared efficiently in a short time, and also its derivatives can be synthesized effectively.

本文言語English
ページ(範囲)1304-1307
ページ数4
ジャーナルAngewandte Chemie - International Edition
48
7
DOI
出版ステータスPublished - 2009 2月 2
外部発表はい

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)

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