Impact of posterior occlusal contact loss on cardiovascular disease using a Japanese claims database

Takashi Miyano, Yudai Tamada, Taro Kusama, Ken Osaka, Kenji Takeuchi

研究成果: ジャーナルへの寄稿学術論文査読

抄録

Cardiovascular disease (CVD) is a global health concern; however, its association with the posterior occlusal contact remains unexplored. This study investigated the association between posterior occlusal contact and CVD risk in a large Japanese cohort and examined whether the loss of posterior occlusal contact in individuals with at least 20 teeth was a distinct CVD risk factor. Using Japanese health insurance claims data from 1,209,997 adults aged ≥ 40 years without prior CVD history (April 2016–March 2022), participants were categorized using the Eichner classification to assess posterior occlusal contact. Over an average follow-up period of 36.2 months, 51,471 participants developed CVD. Compared with individuals with full occlusal contact (Eichner A), those with reduced contact (Eichner B and C) demonstrated significantly higher CVD risks, with hazard ratios of 1.25 (95% confidence interval [CI]: 1.19–1.32) and 1.31 (95% CI: 1.17–1.46), respectively. In a subgroup analysis of participants with ≥ 20 teeth, reduced occlusal contact from Eichner A2 to B2 was associated with an increased risk of CVD, especially in those aged 40–59 years. These findings suggest that reduced posterior occlusal contact may contribute to increased CVD risk, emphasizing the importance of preserving natural occlusal support for CVD prevention.

本文言語英語
論文番号16693
ジャーナルScientific Reports
15
1
DOI
出版ステータス出版済み - 2025 12月

フィンガープリント

「Impact of posterior occlusal contact loss on cardiovascular disease using a Japanese claims database」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル