TY - JOUR
T1 - jMorp
T2 - Japanese Multi-Omics Reference Panel update report 2023
AU - Tadaka, Shu
AU - Kawashima, Junko
AU - Hishinuma, Eiji
AU - Saito, Sakae
AU - Okamura, Yasunobu
AU - Otsuki, Akihito
AU - Kojima, Kaname
AU - Komaki, Shohei
AU - Aoki, Yuichi
AU - Kanno, Takanari
AU - Saigusa, Daisuke
AU - Inoue, Jin
AU - Shirota, Matsuyuki
AU - Takayama, Jun
AU - Katsuoka, Fumiki
AU - Shimizu, Atsushi
AU - Tamiya, Gen
AU - Shimizu, Ritsuko
AU - Hiratsuka, Masahiro
AU - Motoike, Ikuko N.
AU - Koshiba, Seizo
AU - Sasaki, Makoto
AU - Yamamoto, Masayuki
AU - Kinoshita, Kengo
N1 - Publisher Copyright:
© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.
PY - 2024/1/5
Y1 - 2024/1/5
N2 - Modern medicine is increasingly focused on personalized medicine, and multi-omics data is crucial in understanding biological phenomena and disease mechanisms. Each ethnic group has its unique genetic background with specific genomic variations influencing disease risk and drug response. Therefore, multi-omics data from specific ethnic populations are essential for the effective implementation of personalized medicine. Various prospective cohort studies, such as the UK Biobank, All of Us and Lifelines, have been conducted worldwide. The Tohoku Medical Megabank project was initiated after the Great East Japan Earthquake in 2011. It collects biological specimens and conducts genome and omics analyses to build a basis for personalized medicine. Summary statistical data from these analyses are available in the jMorp web database (https://jmorp.megabank.tohoku.ac.jp), which provides a multidimensional approach to the diversity of the Japanese population. jMorp was launched in 2015 as a public database for plasma metabolome and proteome analyses and has been continuously updated. The current update will significantly expand the scale of the data (metabolome, genome, transcriptome, and metagenome). In addition, the user interface and backend server implementations were rewritten to improve the connectivity between the items stored in jMorp. This paper provides an overview of the new version of the jMorp.
AB - Modern medicine is increasingly focused on personalized medicine, and multi-omics data is crucial in understanding biological phenomena and disease mechanisms. Each ethnic group has its unique genetic background with specific genomic variations influencing disease risk and drug response. Therefore, multi-omics data from specific ethnic populations are essential for the effective implementation of personalized medicine. Various prospective cohort studies, such as the UK Biobank, All of Us and Lifelines, have been conducted worldwide. The Tohoku Medical Megabank project was initiated after the Great East Japan Earthquake in 2011. It collects biological specimens and conducts genome and omics analyses to build a basis for personalized medicine. Summary statistical data from these analyses are available in the jMorp web database (https://jmorp.megabank.tohoku.ac.jp), which provides a multidimensional approach to the diversity of the Japanese population. jMorp was launched in 2015 as a public database for plasma metabolome and proteome analyses and has been continuously updated. The current update will significantly expand the scale of the data (metabolome, genome, transcriptome, and metagenome). In addition, the user interface and backend server implementations were rewritten to improve the connectivity between the items stored in jMorp. This paper provides an overview of the new version of the jMorp.
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U2 - 10.1093/nar/gkad978
DO - 10.1093/nar/gkad978
M3 - Article
C2 - 37930845
AN - SCOPUS:85181760729
SN - 0305-1048
VL - 52
SP - D622-D632
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - D1
ER -