Lifestyle changes and outcomes of older adults with mild cognitive impairment: A 4-year longitudinal study

Osamu Katayama, Sangyoon Lee, Seongryu Bae, Keitaro Makino, Yohei Shinkai, Ippei Chiba, Kenji Harada, Hiroyuki Shimada

研究成果: Article査読

8 被引用数 (Scopus)


Longitudinal studies have shown that mild cognitive impairment (MCI) reverts to normal cognition (NC). However, we could not find any reports on the examination of changes in lifestyle activity patterns in older adults diagnosed with MCI and their outcomes, in a longitudinal study. We determined the changes in lifestyle activity patterns among older adults with MCI. Methods: The participants in this study were 769 community-dwelling older adults aged ≥65 years with MCI at baseline. Four years later, participants were categorized into reverters, maintainers, and converters who reverted from MCI to NC, maintained MCI, and had global cognitive impairment or Alzheimer disease, respectively. We used latent class analysis to classify changes in instrumental activities of daily living, and in cognitive, social, and productive activities of the participants. Subsequently, a multinomial logistic regression analysis was performed with reversion status and class membership as the dependent and independent variables, respectively. Results: The reversion rate of 769 participants was 33.3%. The reverters maintained multidomain lifestyle activities, converters discontinued multidomain lifestyle activities or were inactive, and maintainers maintained productive activities. According to the logistic regression analysis, the activity patterns of those who continued to engage in multidomain lifestyle activities and start activities, were more likely to help in reverting from MCI to NC (P < 0.05). Conclusions: Community-dwelling older adults with MCI who continued their multidomain lifestyle activities were more likely to revert to NC. Even if it does not revert to NC, continuing productive activities is important to maintaining MCI without converting.

ジャーナルArchives of Gerontology and Geriatrics
出版ステータスPublished - 2021 5月 1

ASJC Scopus subject areas

  • 健康(社会科学)
  • 加齢科学
  • 老年学
  • 老年医学


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