Matrix Metalloproteinase 28-Bearing Microcystic Adnexal Carcinoma on the Back

Hiromu Chiba, Yumi Kambayashi, Erika Tamabuchi, Akira Hashimoto, Taku Fujimura

研究成果: Article査読

抄録

Although microcystic adnexal carcinoma (MAC) recurs and expands locally without metastases to the lymph nodes and other organs, its biological behavior remains unknown. In this report, a case of a giant MAC on the back treated with radical excision and curative radiation therapy and its characteristic dermoscopic findings are presented. In addition, immunohistochemical staining showed the expression of matrix metalloproteinase (MMP) 28 on the tumor cells and MMP12 and periostin in the stroma. The present case suggests the possible biological behaviors of MAC and might provide a possible target for the treatment of MAC in the future.

本文言語English
ページ(範囲)1773-1778
ページ数6
ジャーナルCase Reports in Oncology
14
3
DOI
出版ステータスPublished - 2021 12月 13
外部発表はい

ASJC Scopus subject areas

  • 腫瘍学

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